Hepatitis C Virus In Children In Beni –Suef Governorate
The aim of this study is to study HCV infection in children in beni-suef governorate and to detect epidemiology and risk factors in studied group. HCV antibodies by4th generation ELISA. , alanine aminotransferase (ALT) levels and aspartate transaminase(AST) were done for children at the age of 6-17y...
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| Format: | Article |
| Language: | English |
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Beni-Suef University, Faculty of Medicine
2022-01-01
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| Series: | Egyptian Journal of Medical Research |
| Subjects: | |
| Online Access: | https://ejmr.journals.ekb.eg/article_222313_601f8819e1c19cce18f7da34acff16fa.pdf |
| _version_ | 1828003619916480512 |
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| author | Abdel Megeed Abdel Megeed Mahmoud Hodeeb Fatma El Zahraa Ahmed |
| author_facet | Abdel Megeed Abdel Megeed Mahmoud Hodeeb Fatma El Zahraa Ahmed |
| author_sort | Abdel Megeed Abdel Megeed |
| collection | DOAJ |
| description | The aim of this study is to study HCV infection in children in beni-suef governorate and to detect epidemiology and risk factors in studied group. HCV antibodies by4th generation ELISA. , alanine aminotransferase (ALT) levels and aspartate transaminase(AST) were done for children at the age of 6-17years . Every child with positive HCV antibodies was tested for HCV RNA by PCR. We studied 47 children positive for HCVantibody . 41 of them were HCV RNA positive and 6 of them had negative HCV RNA.Blood transfusion,frequent iv injection,hospitalization,previous operation,family history of HCV infection,circumcision and ear piercing are significant risk factors for infection.Pallor,jaundice and abdominal distention are common symptoms among HcvAb positive childrens. 100% of negative cases in HCV.Ab analysis were the same in PCR analysis in contrast from positive cases where 87% of positive cases in PCR agreed with HCV.Ab analysis but 13% of cases were negatively infected with HCV.ALT and AST were significantly higher in positive cases with HCVAb and PCR as compared to negative cases. |
| first_indexed | 2024-04-10T07:01:28Z |
| format | Article |
| id | doaj.art-3598b8664f1047bb8449f279f7868326 |
| institution | Directory Open Access Journal |
| issn | 2682-4396 2682-440X |
| language | English |
| last_indexed | 2024-04-10T07:01:28Z |
| publishDate | 2022-01-01 |
| publisher | Beni-Suef University, Faculty of Medicine |
| record_format | Article |
| series | Egyptian Journal of Medical Research |
| spelling | doaj.art-3598b8664f1047bb8449f279f78683262023-02-27T17:41:44ZengBeni-Suef University, Faculty of MedicineEgyptian Journal of Medical Research2682-43962682-440X2022-01-013126227610.21608/ejmr.2022.222313222313Hepatitis C Virus In Children In Beni –Suef GovernorateAbdel Megeed Abdel Megeed0Mahmoud Hodeeb1Fatma El Zahraa Ahmed2Pediatrics department, Faculty Of Medicine,Beni- Suef University.Pediatrics department, Faculty Of Medicine,Beni- Suef University.Pediatrics department, Faculty Of Medicine,Beni- Suef University.The aim of this study is to study HCV infection in children in beni-suef governorate and to detect epidemiology and risk factors in studied group. HCV antibodies by4th generation ELISA. , alanine aminotransferase (ALT) levels and aspartate transaminase(AST) were done for children at the age of 6-17years . Every child with positive HCV antibodies was tested for HCV RNA by PCR. We studied 47 children positive for HCVantibody . 41 of them were HCV RNA positive and 6 of them had negative HCV RNA.Blood transfusion,frequent iv injection,hospitalization,previous operation,family history of HCV infection,circumcision and ear piercing are significant risk factors for infection.Pallor,jaundice and abdominal distention are common symptoms among HcvAb positive childrens. 100% of negative cases in HCV.Ab analysis were the same in PCR analysis in contrast from positive cases where 87% of positive cases in PCR agreed with HCV.Ab analysis but 13% of cases were negatively infected with HCV.ALT and AST were significantly higher in positive cases with HCVAb and PCR as compared to negative cases.https://ejmr.journals.ekb.eg/article_222313_601f8819e1c19cce18f7da34acff16fa.pdfhepatitis cinterferonchildren |
| spellingShingle | Abdel Megeed Abdel Megeed Mahmoud Hodeeb Fatma El Zahraa Ahmed Hepatitis C Virus In Children In Beni –Suef Governorate Egyptian Journal of Medical Research hepatitis c interferon children |
| title | Hepatitis C Virus In Children In Beni –Suef Governorate |
| title_full | Hepatitis C Virus In Children In Beni –Suef Governorate |
| title_fullStr | Hepatitis C Virus In Children In Beni –Suef Governorate |
| title_full_unstemmed | Hepatitis C Virus In Children In Beni –Suef Governorate |
| title_short | Hepatitis C Virus In Children In Beni –Suef Governorate |
| title_sort | hepatitis c virus in children in beni suef governorate |
| topic | hepatitis c interferon children |
| url | https://ejmr.journals.ekb.eg/article_222313_601f8819e1c19cce18f7da34acff16fa.pdf |
| work_keys_str_mv | AT abdelmegeedabdelmegeed hepatitiscvirusinchildreninbenisuefgovernorate AT mahmoudhodeeb hepatitiscvirusinchildreninbenisuefgovernorate AT fatmaelzahraaahmed hepatitiscvirusinchildreninbenisuefgovernorate |