Polymerase chain reaction: A molecular diagnostic tool in periodontology
This review discusses the principles of polymerase chain reaction (PCR) and its application as a diagnostic tool in periodontology. The relevant MEDLINE and PubMed indexed journals were searched manually and electronically by typing PCR, applications of PCR, PCR in periodontics, polymorphism studies...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Journal of Indian Society of Periodontology |
| Subjects: | |
| Online Access: | http://www.jisponline.com/article.asp?issn=0972-124X;year=2016;volume=20;issue=2;spage=128;epage=135;aulast=Maheaswari |
| _version_ | 1819239553586692096 |
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| author | Rajendran Maheaswari Jaishree Tukaram Kshirsagar Nallasivam Lavanya |
| author_facet | Rajendran Maheaswari Jaishree Tukaram Kshirsagar Nallasivam Lavanya |
| author_sort | Rajendran Maheaswari |
| collection | DOAJ |
| description | This review discusses the principles of polymerase chain reaction (PCR) and its application as a diagnostic tool in periodontology. The relevant MEDLINE and PubMed indexed journals were searched manually and electronically by typing PCR, applications of PCR, PCR in periodontics, polymorphism studies in periodontitis, and molecular techniques in periodontology. The searches were limited to articles in English language and the articles describing PCR process and its relation to periodontology were collected and used to prepare a concise review. PCR has now become a standard diagnostic and research tool in periodontology. Various studies reveal that its sensitivity and specificity allow it as a rapid, efficient method of detecting, identifying, and quantifying organism. Different immune and inflammatory markers can be identified at the mRNA expression level, and also the determination of genetic polymorphisms, thus providing the deeper insight into the mechanisms underlying the periodontal disease. |
| first_indexed | 2024-12-23T13:53:57Z |
| format | Article |
| id | doaj.art-359ad917bb544422af407f040722179a |
| institution | Directory Open Access Journal |
| issn | 0972-124X |
| language | English |
| last_indexed | 2024-12-23T13:53:57Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Indian Society of Periodontology |
| spelling | doaj.art-359ad917bb544422af407f040722179a2022-12-21T17:44:31ZengWolters Kluwer Medknow PublicationsJournal of Indian Society of Periodontology0972-124X2016-01-0120212813510.4103/0972-124X.176391Polymerase chain reaction: A molecular diagnostic tool in periodontologyRajendran MaheaswariJaishree Tukaram KshirsagarNallasivam LavanyaThis review discusses the principles of polymerase chain reaction (PCR) and its application as a diagnostic tool in periodontology. The relevant MEDLINE and PubMed indexed journals were searched manually and electronically by typing PCR, applications of PCR, PCR in periodontics, polymorphism studies in periodontitis, and molecular techniques in periodontology. The searches were limited to articles in English language and the articles describing PCR process and its relation to periodontology were collected and used to prepare a concise review. PCR has now become a standard diagnostic and research tool in periodontology. Various studies reveal that its sensitivity and specificity allow it as a rapid, efficient method of detecting, identifying, and quantifying organism. Different immune and inflammatory markers can be identified at the mRNA expression level, and also the determination of genetic polymorphisms, thus providing the deeper insight into the mechanisms underlying the periodontal disease.http://www.jisponline.com/article.asp?issn=0972-124X;year=2016;volume=20;issue=2;spage=128;epage=135;aulast=MaheaswariApplications of polymerase chain reactionidentification of periodontal organismsmolecular techniques in periodontologymRNA expressionpolymerase chain reaction |
| spellingShingle | Rajendran Maheaswari Jaishree Tukaram Kshirsagar Nallasivam Lavanya Polymerase chain reaction: A molecular diagnostic tool in periodontology Journal of Indian Society of Periodontology Applications of polymerase chain reaction identification of periodontal organisms molecular techniques in periodontology mRNA expression polymerase chain reaction |
| title | Polymerase chain reaction: A molecular diagnostic tool in periodontology |
| title_full | Polymerase chain reaction: A molecular diagnostic tool in periodontology |
| title_fullStr | Polymerase chain reaction: A molecular diagnostic tool in periodontology |
| title_full_unstemmed | Polymerase chain reaction: A molecular diagnostic tool in periodontology |
| title_short | Polymerase chain reaction: A molecular diagnostic tool in periodontology |
| title_sort | polymerase chain reaction a molecular diagnostic tool in periodontology |
| topic | Applications of polymerase chain reaction identification of periodontal organisms molecular techniques in periodontology mRNA expression polymerase chain reaction |
| url | http://www.jisponline.com/article.asp?issn=0972-124X;year=2016;volume=20;issue=2;spage=128;epage=135;aulast=Maheaswari |
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