Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics

Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics

Summary: The human leukocyte antigen (HLA)-bound viral antigens serve as an immunological signature that can be selectively recognized by T cells. As viruses evolve by acquiring mutations, it is essential to identify a range of presented viral antigens. Using HLA peptidomics, we are able to identify...

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Bibliographic Details
Main Authors: Adi Nagler, Shelly Kalaora, Chaya Barbolin, Anastasia Gangaev, Steven L.C. Ketelaars, Michal Alon, Joy Pai, Gil Benedek, Yfat Yahalom-Ronen, Noam Erez, Polina Greenberg, Gal Yagel, Aviyah Peri, Yishai Levin, Ansuman T. Satpathy, Erez Bar-Haim, Nir Paran, Pia Kvistborg, Yardena Samuels
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Cell Reports
Subjects:
SARS-CoV-2
HLA
Peptides
Peptidomics
out-of-frame-ORFs
immuno-reactive
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721006811

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