Prevalence of depression, anxiety, adjustment disorders, and somatoform disorders in patients with age-related macular degeneration in Germany
Aims: The purpose of this study was to analyze the prevalence of depression, anxiety, adjustment disorders, and somatoform disorders in patients diagnosed with age-related macular degeneration (AMD) in Germany.Methods: This study included 7,580 patients between the ages of 40 and 90 diagnosed with A...
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| Format: | Article |
| Language: | deu |
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German Medical Science GMS Publishing House
2017-02-01
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| Series: | GMS German Medical Science |
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| Online Access: | http://www.egms.de/static/en/journals/gms/2017-15/000245.shtml |
| _version_ | 1828453127148273664 |
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| author | Jacob, Louis Spiess, Alexandra Kostev, Karel |
| author_facet | Jacob, Louis Spiess, Alexandra Kostev, Karel |
| author_sort | Jacob, Louis |
| collection | DOAJ |
| description | Aims: The purpose of this study was to analyze the prevalence of depression, anxiety, adjustment disorders, and somatoform disorders in patients diagnosed with age-related macular degeneration (AMD) in Germany.Methods: This study included 7,580 patients between the ages of 40 and 90 diagnosed with AMD between January 2011 and December 2014 in 1,072 primary care practices (index date). The last follow-up was in July 2016. We also included 7,580 controls without AMD, which were matched (1:1) to the AMD cases by age, sex, type of health insurance (private or statutory), physician, and Charlson comorbidity score as a generic marker of comorbidity. The outcome of the study was the prevalence of depression, anxiety, adjustment disorders, and somatoform disorders recorded in the database between the index date and the end of follow-up. Results: The mean age among subjects was 75.7 years (SD=10.1 years), 34.0% were men, and 7.8% had private health insurance coverage. The Charlson comorbidity index was 2.0 (SD=1.8). Depression was the most frequent disease (33.7% in AMD patients versus 27.3% in controls), followed by somatoform disorders (19.6% and 16.7%), adjustment disorders (14.8% and 10.5%), and anxiety disorders (11.7% and 8.2%). Depression (OR=1.37, 95% CI: 1.27–1.47), anxiety (OR=1.50, 95% CI: 1.35–1.67), adjustment disorders (OR=1.50, 95% CI: 1.36–1.65), and somatoform disorders (OR=1.22, 95% CI: 1.12–1.32) were all positively associated with AMD. Conclusion: Overall, a significant association was found between AMD and depression, anxiety, adjustment disorders, and somatoform disorders. |
| first_indexed | 2024-12-11T00:02:47Z |
| format | Article |
| id | doaj.art-359f71b7e6954bd4983233f68037e7b6 |
| institution | Directory Open Access Journal |
| issn | 1612-3174 |
| language | deu |
| last_indexed | 2024-12-11T00:02:47Z |
| publishDate | 2017-02-01 |
| publisher | German Medical Science GMS Publishing House |
| record_format | Article |
| series | GMS German Medical Science |
| spelling | doaj.art-359f71b7e6954bd4983233f68037e7b62022-12-22T01:28:24ZdeuGerman Medical Science GMS Publishing HouseGMS German Medical Science1612-31742017-02-0115Doc0410.3205/000245Prevalence of depression, anxiety, adjustment disorders, and somatoform disorders in patients with age-related macular degeneration in GermanyJacob, Louis0Spiess, Alexandra1Kostev, Karel2Faculty of Medicine, University of Paris 5, Paris, FranceIMS Health, Frankfurt, GermanyIMS Health, Frankfurt, GermanyAims: The purpose of this study was to analyze the prevalence of depression, anxiety, adjustment disorders, and somatoform disorders in patients diagnosed with age-related macular degeneration (AMD) in Germany.Methods: This study included 7,580 patients between the ages of 40 and 90 diagnosed with AMD between January 2011 and December 2014 in 1,072 primary care practices (index date). The last follow-up was in July 2016. We also included 7,580 controls without AMD, which were matched (1:1) to the AMD cases by age, sex, type of health insurance (private or statutory), physician, and Charlson comorbidity score as a generic marker of comorbidity. The outcome of the study was the prevalence of depression, anxiety, adjustment disorders, and somatoform disorders recorded in the database between the index date and the end of follow-up. Results: The mean age among subjects was 75.7 years (SD=10.1 years), 34.0% were men, and 7.8% had private health insurance coverage. The Charlson comorbidity index was 2.0 (SD=1.8). Depression was the most frequent disease (33.7% in AMD patients versus 27.3% in controls), followed by somatoform disorders (19.6% and 16.7%), adjustment disorders (14.8% and 10.5%), and anxiety disorders (11.7% and 8.2%). Depression (OR=1.37, 95% CI: 1.27–1.47), anxiety (OR=1.50, 95% CI: 1.35–1.67), adjustment disorders (OR=1.50, 95% CI: 1.36–1.65), and somatoform disorders (OR=1.22, 95% CI: 1.12–1.32) were all positively associated with AMD. Conclusion: Overall, a significant association was found between AMD and depression, anxiety, adjustment disorders, and somatoform disorders.http://www.egms.de/static/en/journals/gms/2017-15/000245.shtmlage-related macular degenerationdepressionanxietyadjustment disordersomatoform disorder |
| spellingShingle | Jacob, Louis Spiess, Alexandra Kostev, Karel Prevalence of depression, anxiety, adjustment disorders, and somatoform disorders in patients with age-related macular degeneration in Germany GMS German Medical Science age-related macular degeneration depression anxiety adjustment disorder somatoform disorder |
| title | Prevalence of depression, anxiety, adjustment disorders, and somatoform disorders in patients with age-related macular degeneration in Germany |
| title_full | Prevalence of depression, anxiety, adjustment disorders, and somatoform disorders in patients with age-related macular degeneration in Germany |
| title_fullStr | Prevalence of depression, anxiety, adjustment disorders, and somatoform disorders in patients with age-related macular degeneration in Germany |
| title_full_unstemmed | Prevalence of depression, anxiety, adjustment disorders, and somatoform disorders in patients with age-related macular degeneration in Germany |
| title_short | Prevalence of depression, anxiety, adjustment disorders, and somatoform disorders in patients with age-related macular degeneration in Germany |
| title_sort | prevalence of depression anxiety adjustment disorders and somatoform disorders in patients with age related macular degeneration in germany |
| topic | age-related macular degeneration depression anxiety adjustment disorder somatoform disorder |
| url | http://www.egms.de/static/en/journals/gms/2017-15/000245.shtml |
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