Exercise as a potential treatment for drug abuse: Evidence from preclinical studies
Epidemiological studies reveal that individuals who engage in regular aerobic exercise are less likely to use and abuse illicit drugs. Until recently, very few studies had examined the causal influences that mediate this relationship, and it was not clear whether exercise was effective at reducing s...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2012-01-01
|
| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fpsyt.2011.00082/full |
| _version_ | 1818608026158891008 |
|---|---|
| author | Mark Andrew Smith Wendy J Lynch |
| author_facet | Mark Andrew Smith Wendy J Lynch |
| author_sort | Mark Andrew Smith |
| collection | DOAJ |
| description | Epidemiological studies reveal that individuals who engage in regular aerobic exercise are less likely to use and abuse illicit drugs. Until recently, very few studies had examined the causal influences that mediate this relationship, and it was not clear whether exercise was effective at reducing substance use and abuse. In the past few years, several preclinical studies have revealed that exercise reduces drug self-administration in laboratory animals. These studies have revealed that exercise produces protective effects in procedures designed to model different transitional phases that occur during the development of, and recover from, a substance use disorder (e.g., acquisition, maintenance, escalation, and relapse/reinstatement of drug use). Moreover, recent studies have revealed several behavioral and neurobiological consequences of exercise that may be responsible for its protective effects in these assays. Collectively, these studies have provided convincing evidence to support the development of exercise-based interventions to reduce compulsive patterns of drug intake in clinical and at-risk populations. |
| first_indexed | 2024-12-16T14:36:06Z |
| format | Article |
| id | doaj.art-359f919048e34c42a8a52126136b2d4d |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-12-16T14:36:06Z |
| publishDate | 2012-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-359f919048e34c42a8a52126136b2d4d2022-12-21T22:28:06ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402012-01-01210.3389/fpsyt.2011.0008218925Exercise as a potential treatment for drug abuse: Evidence from preclinical studiesMark Andrew Smith0Wendy J Lynch1Davidson CollegeUniversity of VirginiaEpidemiological studies reveal that individuals who engage in regular aerobic exercise are less likely to use and abuse illicit drugs. Until recently, very few studies had examined the causal influences that mediate this relationship, and it was not clear whether exercise was effective at reducing substance use and abuse. In the past few years, several preclinical studies have revealed that exercise reduces drug self-administration in laboratory animals. These studies have revealed that exercise produces protective effects in procedures designed to model different transitional phases that occur during the development of, and recover from, a substance use disorder (e.g., acquisition, maintenance, escalation, and relapse/reinstatement of drug use). Moreover, recent studies have revealed several behavioral and neurobiological consequences of exercise that may be responsible for its protective effects in these assays. Collectively, these studies have provided convincing evidence to support the development of exercise-based interventions to reduce compulsive patterns of drug intake in clinical and at-risk populations.http://journal.frontiersin.org/Journal/10.3389/fpsyt.2011.00082/fullDrug-Seeking Behaviorphysical activityaerobic exercisedrug self-administration |
| spellingShingle | Mark Andrew Smith Wendy J Lynch Exercise as a potential treatment for drug abuse: Evidence from preclinical studies Frontiers in Psychiatry Drug-Seeking Behavior physical activity aerobic exercise drug self-administration |
| title | Exercise as a potential treatment for drug abuse: Evidence from preclinical studies |
| title_full | Exercise as a potential treatment for drug abuse: Evidence from preclinical studies |
| title_fullStr | Exercise as a potential treatment for drug abuse: Evidence from preclinical studies |
| title_full_unstemmed | Exercise as a potential treatment for drug abuse: Evidence from preclinical studies |
| title_short | Exercise as a potential treatment for drug abuse: Evidence from preclinical studies |
| title_sort | exercise as a potential treatment for drug abuse evidence from preclinical studies |
| topic | Drug-Seeking Behavior physical activity aerobic exercise drug self-administration |
| url | http://journal.frontiersin.org/Journal/10.3389/fpsyt.2011.00082/full |
| work_keys_str_mv | AT markandrewsmith exerciseasapotentialtreatmentfordrugabuseevidencefrompreclinicalstudies AT wendyjlynch exerciseasapotentialtreatmentfordrugabuseevidencefrompreclinicalstudies |