Marine Antitumor Peptide Dolastatin 10: Biological Activity, Structural Modification and Synthetic Chemistry
Dolastatin 10 (Dol-10), a leading marine pentapeptide isolated from the Indian Ocean mollusk <i>Dolabella auricularia</i>, contains three unique amino acid residues. Dol-10 can effectively induce apoptosis of lung cancer cells and other tumor cells at nanomolar concentration, and it has...
Main Authors: | Gang Gao, Yanbing Wang, Huiming Hua, Dahong Li, Chunlan Tang |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-06-01
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Series: | Marine Drugs |
Subjects: | |
Online Access: | https://www.mdpi.com/1660-3397/19/7/363 |
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