Efficacy and Safety of Giant Condyloma Acuminatum with Monotherapy of Topical Traditional Chinese Medicine: Report of Eight Cases
Mei-fang Wang, Li Lin, Lin-feng Li Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People’s Republic of ChinaCorrespondence: Lin-feng LiDepartment of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050,...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2021-04-01
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| Series: | Infection and Drug Resistance |
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| Online Access: | https://www.dovepress.com/efficacy-and-safety-of-giant-condyloma-acuminatum-with-monotherapy-of--peer-reviewed-article-IDR |
| _version_ | 1818456590199554048 |
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| author | Wang M Lin L Li L |
| author_facet | Wang M Lin L Li L |
| author_sort | Wang M |
| collection | DOAJ |
| description | Mei-fang Wang, Li Lin, Lin-feng Li Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People’s Republic of ChinaCorrespondence: Lin-feng LiDepartment of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People’s Republic of ChinaTel +8613693620186Email zoonli@sina.comBackground: Giant condyloma acuminatum (GCA), also called Buschke–Löwenstein tumor, presents as a verrucous infiltrating lesion and is caused by sexual transmission of human papilloma virus. The optimal treatment is controversial and there are no standard guidelines because of its rarity and frequent recurrence. It has a relatively high local recurrence rate.Objective: We here report eight patients (six men and two women) with GCA whose lesions were successfully treated topically with traditional Chinese medicine (TCM) preparations, paiteling.Methods and Materials: We administered topical TCM preparations to eight patients diagnosed with GCA who had refused surgery. The treatment process included three stages, their durations depending on the speed of resolution of the lesions and the results of visual inspection with acetic acid.Results: No significant complications occurred in any patient. The functional and esthetic outcomes were satisfactory. No recurrences were detected during follow-up.Conclusion: Topical treatment with TCM preparations may be a good alternative to surgery or other traditional methods for the treatment of GCA. This treatment has the advantages of being non-invasive, painless, and having a low risk of recurrence, and may be a useful adjunct to mainstream medical treatments.Keywords: giant condyloma acuminatum, GCA, traditional Chinese medicine, TCM, treatment, dermatosis symptoms, paiteling |
| first_indexed | 2024-12-14T22:29:05Z |
| format | Article |
| id | doaj.art-35a2e1c2069d4c7d83f0aa59676a23a4 |
| institution | Directory Open Access Journal |
| issn | 1178-6973 |
| language | English |
| last_indexed | 2024-12-14T22:29:05Z |
| publishDate | 2021-04-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Infection and Drug Resistance |
| spelling | doaj.art-35a2e1c2069d4c7d83f0aa59676a23a42022-12-21T22:45:17ZengDove Medical PressInfection and Drug Resistance1178-69732021-04-01Volume 141375137963758Efficacy and Safety of Giant Condyloma Acuminatum with Monotherapy of Topical Traditional Chinese Medicine: Report of Eight CasesWang MLin LLi LMei-fang Wang, Li Lin, Lin-feng Li Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People’s Republic of ChinaCorrespondence: Lin-feng LiDepartment of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People’s Republic of ChinaTel +8613693620186Email zoonli@sina.comBackground: Giant condyloma acuminatum (GCA), also called Buschke–Löwenstein tumor, presents as a verrucous infiltrating lesion and is caused by sexual transmission of human papilloma virus. The optimal treatment is controversial and there are no standard guidelines because of its rarity and frequent recurrence. It has a relatively high local recurrence rate.Objective: We here report eight patients (six men and two women) with GCA whose lesions were successfully treated topically with traditional Chinese medicine (TCM) preparations, paiteling.Methods and Materials: We administered topical TCM preparations to eight patients diagnosed with GCA who had refused surgery. The treatment process included three stages, their durations depending on the speed of resolution of the lesions and the results of visual inspection with acetic acid.Results: No significant complications occurred in any patient. The functional and esthetic outcomes were satisfactory. No recurrences were detected during follow-up.Conclusion: Topical treatment with TCM preparations may be a good alternative to surgery or other traditional methods for the treatment of GCA. This treatment has the advantages of being non-invasive, painless, and having a low risk of recurrence, and may be a useful adjunct to mainstream medical treatments.Keywords: giant condyloma acuminatum, GCA, traditional Chinese medicine, TCM, treatment, dermatosis symptoms, paitelinghttps://www.dovepress.com/efficacy-and-safety-of-giant-condyloma-acuminatum-with-monotherapy-of--peer-reviewed-article-IDRgiant condyloma acuminatum (gca)traditional chinese medicine (tcm)treatmentdermatosis symptomspaiteling |
| spellingShingle | Wang M Lin L Li L Efficacy and Safety of Giant Condyloma Acuminatum with Monotherapy of Topical Traditional Chinese Medicine: Report of Eight Cases Infection and Drug Resistance giant condyloma acuminatum (gca) traditional chinese medicine (tcm) treatment dermatosis symptoms paiteling |
| title | Efficacy and Safety of Giant Condyloma Acuminatum with Monotherapy of Topical Traditional Chinese Medicine: Report of Eight Cases |
| title_full | Efficacy and Safety of Giant Condyloma Acuminatum with Monotherapy of Topical Traditional Chinese Medicine: Report of Eight Cases |
| title_fullStr | Efficacy and Safety of Giant Condyloma Acuminatum with Monotherapy of Topical Traditional Chinese Medicine: Report of Eight Cases |
| title_full_unstemmed | Efficacy and Safety of Giant Condyloma Acuminatum with Monotherapy of Topical Traditional Chinese Medicine: Report of Eight Cases |
| title_short | Efficacy and Safety of Giant Condyloma Acuminatum with Monotherapy of Topical Traditional Chinese Medicine: Report of Eight Cases |
| title_sort | efficacy and safety of giant condyloma acuminatum with monotherapy of topical traditional chinese medicine report of eight cases |
| topic | giant condyloma acuminatum (gca) traditional chinese medicine (tcm) treatment dermatosis symptoms paiteling |
| url | https://www.dovepress.com/efficacy-and-safety-of-giant-condyloma-acuminatum-with-monotherapy-of--peer-reviewed-article-IDR |
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