Cellular sensitivity of white blood cell in vitro to interferon-α2 in the dynamics of ebv-infections in children
In this study, the cellular sensitivity of white blood cells in vitro to interferon-α2 in children with EBV-infection in the acute period of the disease in terms of the 1, 6, 12 months after a previous infection. Found that children in the dynamics of the EBV-infection, preservation of cell sensitiv...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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Journal Infectology
2014-09-01
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| Series: | Журнал инфектологии |
| Subjects: | |
| Online Access: | https://journal.niidi.ru/jofin/article/view/165 |
| _version_ | 1797702619621228544 |
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| author | M. B. Dryganova G. P. Martynova L. M. Kurtasova S. V. Evreimova |
| author_facet | M. B. Dryganova G. P. Martynova L. M. Kurtasova S. V. Evreimova |
| author_sort | M. B. Dryganova |
| collection | DOAJ |
| description | In this study, the cellular sensitivity of white blood cells in vitro to interferon-α2 in children with EBV-infection in the acute period of the disease in terms of the 1, 6, 12 months after a previous infection. Found that children in the dynamics of the EBV-infection, preservation of cell sensitivity at the same level at 1 month after the disease is seen in 40,5% children, 6 months – 27,8% patients. Lack of cell sensitivity to interferon-α2 blood leukocytes in 12 months after undergoing a EBV-infection observed in 88,9% of children. During repeated courses interferon-therapy to study cellular sensitivity of blood leukocytes for individual selection of the drug. |
| first_indexed | 2024-03-12T04:52:41Z |
| format | Article |
| id | doaj.art-35a3bec27c4349c2bb2da3ed8e751402 |
| institution | Directory Open Access Journal |
| issn | 2072-6732 |
| language | Russian |
| last_indexed | 2024-03-12T04:52:41Z |
| publishDate | 2014-09-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj.art-35a3bec27c4349c2bb2da3ed8e7514022023-09-03T09:18:10ZrusJournal InfectologyЖурнал инфектологии2072-67322014-09-0152323610.22625/2072-6732-2013-5-2-32-36179Cellular sensitivity of white blood cell in vitro to interferon-α2 in the dynamics of ebv-infections in childrenM. B. Dryganova0G. P. Martynova1L. M. Kurtasova2S. V. Evreimova3Красноярский государственный медицинский университет им. профессора В.Ф. Войно-Ясенецкого, КрасноярскКрасноярский государственный медицинский университет им. профессора В.Ф. Войно-Ясенецкого, КрасноярскКрасноярский государственный медицинский университет им. профессора В.Ф. Войно-Ясенецкого, КрасноярскГородская детская клиническая больница № 1, КрасноярскIn this study, the cellular sensitivity of white blood cells in vitro to interferon-α2 in children with EBV-infection in the acute period of the disease in terms of the 1, 6, 12 months after a previous infection. Found that children in the dynamics of the EBV-infection, preservation of cell sensitivity at the same level at 1 month after the disease is seen in 40,5% children, 6 months – 27,8% patients. Lack of cell sensitivity to interferon-α2 blood leukocytes in 12 months after undergoing a EBV-infection observed in 88,9% of children. During repeated courses interferon-therapy to study cellular sensitivity of blood leukocytes for individual selection of the drug.https://journal.niidi.ru/jofin/article/view/165вирусная инфекция эпштейна – баррклеточная чувствительностьинтерферонлейкоциты кровидети |
| spellingShingle | M. B. Dryganova G. P. Martynova L. M. Kurtasova S. V. Evreimova Cellular sensitivity of white blood cell in vitro to interferon-α2 in the dynamics of ebv-infections in children Журнал инфектологии вирусная инфекция эпштейна – барр клеточная чувствительность интерферон лейкоциты крови дети |
| title | Cellular sensitivity of white blood cell in vitro to interferon-α2 in the dynamics of ebv-infections in children |
| title_full | Cellular sensitivity of white blood cell in vitro to interferon-α2 in the dynamics of ebv-infections in children |
| title_fullStr | Cellular sensitivity of white blood cell in vitro to interferon-α2 in the dynamics of ebv-infections in children |
| title_full_unstemmed | Cellular sensitivity of white blood cell in vitro to interferon-α2 in the dynamics of ebv-infections in children |
| title_short | Cellular sensitivity of white blood cell in vitro to interferon-α2 in the dynamics of ebv-infections in children |
| title_sort | cellular sensitivity of white blood cell in vitro to interferon α2 in the dynamics of ebv infections in children |
| topic | вирусная инфекция эпштейна – барр клеточная чувствительность интерферон лейкоциты крови дети |
| url | https://journal.niidi.ru/jofin/article/view/165 |
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