Solubility, Stability, and Avidity of Recombinant Antibody Fragments Expressed in Microorganisms

Solubility, Stability, and Avidity of Recombinant Antibody Fragments Expressed in Microorganisms

Solubility of recombinant proteins (i.e., the extent of soluble versus insoluble expression in heterogeneous hosts) is the first checkpoint criterion for determining recombinant protein quality. However, even soluble proteins often fail to represent functional activity because of the involvement of...

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Bibliographic Details
Main Authors: Tae Hyun Kang, Baik Lin Seong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Microbiology
Subjects:
antibody fragments
solubility
stability
bacterial expression
scFv
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01927/full

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