The Lipid Raft Component Stomatin Interacts with the Na<sup>+</sup> Taurocholate Cotransporting Polypeptide (NTCP) and Modulates Bile Salt Uptake

The Lipid Raft Component Stomatin Interacts with the Na<sup>+</sup> Taurocholate Cotransporting Polypeptide (NTCP) and Modulates Bile Salt Uptake

The sodium taurocholate cotransporting polypeptide (NTCP) is expressed at the basolateral membrane of hepatocytes, where it mediates the uptake of conjugated bile acids and forms the hepatocyte entry receptor for the hepatitis B and D virus. Here, we aimed to identify novel protein–protein interacti...

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Bibliographic Details
Main Authors: Monique D. Appelman, Marion J.D. Robin, Esther W.M. Vogels, Christie Wolzak, Winnie G. Vos, Harmjan R. Vos, Robert M. Van Es, Boudewijn M.T. Burgering, Stan F.J. Van de Graaf
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
bile acid
lipid raft
enterohepatic circulation
cholestasis
ASBT
BSEP
Online Access:https://www.mdpi.com/2073-4409/9/4/986

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