Animal Models of Human Disease

The use of animal models of human disease is critical for furthering our understanding of disease mechanisms, for the discovery of novel targets for treatment, and for translational research. This Special Topic entitled “Animal Models of Human Disease” aimed to collect state-of-the-art primary resea...

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Main Authors: Sigrun Lange, Jameel M. Inal
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/21/15821
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author Sigrun Lange
Jameel M. Inal
author_facet Sigrun Lange
Jameel M. Inal
author_sort Sigrun Lange
collection DOAJ
description The use of animal models of human disease is critical for furthering our understanding of disease mechanisms, for the discovery of novel targets for treatment, and for translational research. This Special Topic entitled “Animal Models of Human Disease” aimed to collect state-of-the-art primary research studies and review articles from international experts and leading groups using animal models to study human diseases. Submissions were welcomed on a wide range of animal models and pathologies, including infectious disease, acute injury, regeneration, cancer, autoimmunity, degenerative and chronic disease. Seven participating MDPI journals supported the Special Topic, namely: <i>Biomedicines</i>, <i>Cells</i>, <i>Current Issues in Molecular Biology</i>, <i>Diagnostics</i>, <i>Genes</i>, the <i>International Journal of Molecular Sciences</i>, and the <i>International Journal of Translational Medicine</i>. In total, 46 papers were published in this Special Topic, with 37 full length original research papers, 2 research communications and 7 reviews. These contributions cover a wide range of clinically relevant, translatable, and comparative animal models, as well as furthering understanding of fundamental sciences, covering topics on physiological processes, on degenerative, inflammatory, infectious, autoimmune, neurological, metabolic, heamatological, hormonal and mitochondrial disorders, developmental processes and diseases, cardiology, cancer, trauma, stress, and ageing.
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spelling doaj.art-35a89446b8e640e4811b31589bcb1f952023-11-10T15:05:25ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-10-0124211582110.3390/ijms242115821Animal Models of Human DiseaseSigrun Lange0Jameel M. Inal1Tissue Architecture and Regeneration Research Group, Department of Biomedical Sciences, University of Westminster, London W1W 6UW, UKCell Communication in Disease Pathology, School of Human Sciences, London Metropolitan University, London N7 8DB, UKThe use of animal models of human disease is critical for furthering our understanding of disease mechanisms, for the discovery of novel targets for treatment, and for translational research. This Special Topic entitled “Animal Models of Human Disease” aimed to collect state-of-the-art primary research studies and review articles from international experts and leading groups using animal models to study human diseases. Submissions were welcomed on a wide range of animal models and pathologies, including infectious disease, acute injury, regeneration, cancer, autoimmunity, degenerative and chronic disease. Seven participating MDPI journals supported the Special Topic, namely: <i>Biomedicines</i>, <i>Cells</i>, <i>Current Issues in Molecular Biology</i>, <i>Diagnostics</i>, <i>Genes</i>, the <i>International Journal of Molecular Sciences</i>, and the <i>International Journal of Translational Medicine</i>. In total, 46 papers were published in this Special Topic, with 37 full length original research papers, 2 research communications and 7 reviews. These contributions cover a wide range of clinically relevant, translatable, and comparative animal models, as well as furthering understanding of fundamental sciences, covering topics on physiological processes, on degenerative, inflammatory, infectious, autoimmune, neurological, metabolic, heamatological, hormonal and mitochondrial disorders, developmental processes and diseases, cardiology, cancer, trauma, stress, and ageing.https://www.mdpi.com/1422-0067/24/21/15821animal modelspathobiologychronic diseaseregenerationinfectious diseasecancer
spellingShingle Sigrun Lange
Jameel M. Inal
Animal Models of Human Disease
International Journal of Molecular Sciences
animal models
pathobiology
chronic disease
regeneration
infectious disease
cancer
title Animal Models of Human Disease
title_full Animal Models of Human Disease
title_fullStr Animal Models of Human Disease
title_full_unstemmed Animal Models of Human Disease
title_short Animal Models of Human Disease
title_sort animal models of human disease
topic animal models
pathobiology
chronic disease
regeneration
infectious disease
cancer
url https://www.mdpi.com/1422-0067/24/21/15821
work_keys_str_mv AT sigrunlange animalmodelsofhumandisease
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