Ancestral sequence reconstruction as a tool to study the evolution of wood decaying fungi
The study of evolution is limited by the techniques available to do so. Aside from the use of the fossil record, molecular phylogenetics can provide a detailed characterization of evolutionary histories using genes, genomes and proteins. However, these tools provide scarce biochemical information of...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Fungal Biology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/ffunb.2022.1003489/full |
| _version_ | 1811339811496132608 |
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| author | Iván Ayuso-Fernández Gonzalo Molpeceres Susana Camarero Francisco Javier Ruiz-Dueñas Angel T. Martínez |
| author_facet | Iván Ayuso-Fernández Gonzalo Molpeceres Susana Camarero Francisco Javier Ruiz-Dueñas Angel T. Martínez |
| author_sort | Iván Ayuso-Fernández |
| collection | DOAJ |
| description | The study of evolution is limited by the techniques available to do so. Aside from the use of the fossil record, molecular phylogenetics can provide a detailed characterization of evolutionary histories using genes, genomes and proteins. However, these tools provide scarce biochemical information of the organisms and systems of interest and are therefore very limited when they come to explain protein evolution. In the past decade, this limitation has been overcome by the development of ancestral sequence reconstruction (ASR) methods. ASR allows the subsequent resurrection in the laboratory of inferred proteins from now extinct organisms, becoming an outstanding tool to study enzyme evolution. Here we review the recent advances in ASR methods and their application to study fungal evolution, with special focus on wood-decay fungi as essential organisms in the global carbon cycling. |
| first_indexed | 2024-04-13T18:32:05Z |
| format | Article |
| id | doaj.art-35a9511af6d645da857d08dce0d73ac0 |
| institution | Directory Open Access Journal |
| issn | 2673-6128 |
| language | English |
| last_indexed | 2024-04-13T18:32:05Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Fungal Biology |
| spelling | doaj.art-35a9511af6d645da857d08dce0d73ac02022-12-22T02:35:01ZengFrontiers Media S.A.Frontiers in Fungal Biology2673-61282022-10-01310.3389/ffunb.2022.10034891003489Ancestral sequence reconstruction as a tool to study the evolution of wood decaying fungiIván Ayuso-Fernández0Gonzalo Molpeceres1Susana Camarero2Francisco Javier Ruiz-Dueñas3Angel T. Martínez4Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences (NMBU), Ås, NorwayCentro de Investigaciones Biológicas “Margarita Salas” (CIB), CSIC, Madrid, SpainCentro de Investigaciones Biológicas “Margarita Salas” (CIB), CSIC, Madrid, SpainCentro de Investigaciones Biológicas “Margarita Salas” (CIB), CSIC, Madrid, SpainCentro de Investigaciones Biológicas “Margarita Salas” (CIB), CSIC, Madrid, SpainThe study of evolution is limited by the techniques available to do so. Aside from the use of the fossil record, molecular phylogenetics can provide a detailed characterization of evolutionary histories using genes, genomes and proteins. However, these tools provide scarce biochemical information of the organisms and systems of interest and are therefore very limited when they come to explain protein evolution. In the past decade, this limitation has been overcome by the development of ancestral sequence reconstruction (ASR) methods. ASR allows the subsequent resurrection in the laboratory of inferred proteins from now extinct organisms, becoming an outstanding tool to study enzyme evolution. Here we review the recent advances in ASR methods and their application to study fungal evolution, with special focus on wood-decay fungi as essential organisms in the global carbon cycling.https://www.frontiersin.org/articles/10.3389/ffunb.2022.1003489/fullancestral sequence reconstructionwood decay fungilignocellulosic biomassplant cell-wall degrading enzymes (PCWDE)evolution |
| spellingShingle | Iván Ayuso-Fernández Gonzalo Molpeceres Susana Camarero Francisco Javier Ruiz-Dueñas Angel T. Martínez Ancestral sequence reconstruction as a tool to study the evolution of wood decaying fungi Frontiers in Fungal Biology ancestral sequence reconstruction wood decay fungi lignocellulosic biomass plant cell-wall degrading enzymes (PCWDE) evolution |
| title | Ancestral sequence reconstruction as a tool to study the evolution of wood decaying fungi |
| title_full | Ancestral sequence reconstruction as a tool to study the evolution of wood decaying fungi |
| title_fullStr | Ancestral sequence reconstruction as a tool to study the evolution of wood decaying fungi |
| title_full_unstemmed | Ancestral sequence reconstruction as a tool to study the evolution of wood decaying fungi |
| title_short | Ancestral sequence reconstruction as a tool to study the evolution of wood decaying fungi |
| title_sort | ancestral sequence reconstruction as a tool to study the evolution of wood decaying fungi |
| topic | ancestral sequence reconstruction wood decay fungi lignocellulosic biomass plant cell-wall degrading enzymes (PCWDE) evolution |
| url | https://www.frontiersin.org/articles/10.3389/ffunb.2022.1003489/full |
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