High glucose-induced apoptosis in human coronary artery endothelial cells involves up-regulation of death receptors

<p>Abstract</p> <p>Background</p> <p>High glucose can induce apoptosis in vascular endothelial cells, which may contribute to the development of vascular complications in diabetes. We evaluated the role of the death receptor pathway of apoptotic signaling in high glucos...

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Bibliographic Details
Main Authors: Yamamoto Seiji, Matsuda Naoyuki, Uchimido Ryo, Kageyama-Yahara Natsuko, Tomita Kengo, Yokoo Hiroki, Kageyama Shun-ichiro, Hattori Yuichi
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Cardiovascular Diabetology
Online Access:http://www.cardiab.com/content/10/1/73