Independent Candidate Serum Protein Biomarkers of Response to Adalimumab and to Infliximab in Rheumatoid Arthritis: An Exploratory Study.

Response to treatment of rheumatoid arthritis shows large inter-individual variability. This heterogeneity is observed with all the anti-rheumatic drugs, including the commonly used TNF inhibitors. It seems that drug-specific and target-specific factors lead individual patients to respond or not to...

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Main Authors: Ignacio Ortea, Bernd Roschitzki, Rosario López-Rodríguez, Eva G Tomero, Juan G Ovalles, Javier López-Longo, Inmaculada de la Torre, Isidoro González-Alvaro, Juan J Gómez-Reino, Antonio González
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4822871?pdf=render