Data-adaptive image-denoising for detecting and quantifying nanoparticle entry in mucosal tissues through intravital 2-photon microscopy
Intravital 2-photon microscopy of mucosal membranes across which nanoparticles enter the organism typically generates noisy images. Because the noise results from the random statistics of only very few photons detected per pixel, it cannot be avoided by technical means. Fluorescent nanoparticles con...
Main Authors: | Torsten Bölke, Lisa Krapf, Regina Orzekowsky-Schroeder, Tobias Vossmeyer, Jelena Dimitrijevic, Horst Weller, Anna Schüth, Antje Klinger, Gereon Hüttmann, Andreas Gebert |
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Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2014-11-01
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Series: | Beilstein Journal of Nanotechnology |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjnano.5.210 |
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