Classification of Cells in CTC-Enriched Samples by Advanced Image Analysis
In the CellSearch® system, blood is immunomagnetically enriched for epithelial cell adhesion molecule (EpCAM) expression and cells are stained with the nucleic acid dye 4′6-diamidino-2-phenylindole (DAPI), Cytokeratin-PE (CK), and CD45-APC. Only DAPI+/CK+ objects are presented to t...
Main Authors: | Sanne de Wit, Leonie L. Zeune, T. Jeroen N. Hiltermann, Harry J. M. Groen, Guus van Dalum, Leon W. M. M. Terstappen |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-10-01
|
Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/10/10/377 |
Similar Items
-
Leukocyte-Derived Extracellular Vesicles in Blood with and without EpCAM Enrichment
by: Afroditi Nanou, et al.
Published: (2019-08-01) -
Towards the Biological Understanding of CTC: Capture Technologies, Definitions and Potential to Create Metastasis
by: Ana M.C. Barradas, et al.
Published: (2013-12-01) -
Comparison of circulating tumor cell (CTC) detection rates with epithelial cell adhesion molecule (EpCAM) and cell surface vimentin (CSV) antibodies in different solid tumors: a retrospective study
by: Yang Gao, et al.
Published: (2021-03-01) -
Circulating tumor cells: the substrate of personalized medicine?
by: Bryan eGreene, et al.
Published: (2012-07-01) -
Frequency of Circulating Tumor Cells (CTC) in Patients with Brain Metastases: Implications as a Risk Assessment Marker in Oligo-Metastatic Disease
by: Annkathrin Hanssen, et al.
Published: (2018-12-01)