Tandem Repeat Diversity in Two Closely Related Hamster Species—The Chinese Hamster (<i>Cricetulus griseus</i>) and Striped Hamster (<i>Cricetulus barabensis</i>)
The Chinese hamster (<i>Cricetulus griseus</i>) and striped hamster (<i>Cricetulus barabensis</i>) are very closely related species with similar karyotypes. The karyotypes differ from each other by one Robertsonian rearrangement and X-chromosome morphology. The level of the t...
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MDPI AG
2022-04-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/10/4/925 |
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| author | Nadezhda G. Ivanova Irina V. Kartavtseva Vera N. Stefanova Dmitrii I. Ostromyshenskii Olga I. Podgornaya |
| author_facet | Nadezhda G. Ivanova Irina V. Kartavtseva Vera N. Stefanova Dmitrii I. Ostromyshenskii Olga I. Podgornaya |
| author_sort | Nadezhda G. Ivanova |
| collection | DOAJ |
| description | The Chinese hamster (<i>Cricetulus griseus</i>) and striped hamster (<i>Cricetulus barabensis</i>) are very closely related species with similar karyotypes. The karyotypes differ from each other by one Robertsonian rearrangement and X-chromosome morphology. The level of the tandem repeat (TR) sequences’ evolutional variability is high. The aim of the current work was to trace the TR distribution on the chromosomes of two very closely related species. The striped hamster genome has not yet been sequenced. We classified the Chinese hamster TR in the assemblies available and then compared the mode of the TR distribution in closely related species. Chinese and striped hamsters are separate species due to the relative species specificity of Chinese hamster TR and prominent differences in the TR distribution in both species. The TR variation observed within homologous striped hamster chromosomes is caused by a lack of inbreeding in natural populations. The set of TR tested could be used to examine the CHO lines’ instability that has been observed in heterochromatic regions. |
| first_indexed | 2024-03-09T11:05:57Z |
| format | Article |
| id | doaj.art-35bd69c1134b4b7da3337540be764141 |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-09T11:05:57Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-35bd69c1134b4b7da3337540be7641412023-12-01T00:56:38ZengMDPI AGBiomedicines2227-90592022-04-0110492510.3390/biomedicines10040925Tandem Repeat Diversity in Two Closely Related Hamster Species—The Chinese Hamster (<i>Cricetulus griseus</i>) and Striped Hamster (<i>Cricetulus barabensis</i>)Nadezhda G. Ivanova0Irina V. Kartavtseva1Vera N. Stefanova2Dmitrii I. Ostromyshenskii3Olga I. Podgornaya4Laboratory of Noncoding DNA, Institute of Cytology RAS, Saint Petersburg 194064, RussiaLaboratory of Evolutionary Zoology, Federal Scientific Center of the East Asia Terrestrial Biodiversity, Vladivostok 690022, RussiaLaboratory of Noncoding DNA, Institute of Cytology RAS, Saint Petersburg 194064, RussiaLaboratory of Noncoding DNA, Institute of Cytology RAS, Saint Petersburg 194064, RussiaLaboratory of Noncoding DNA, Institute of Cytology RAS, Saint Petersburg 194064, RussiaThe Chinese hamster (<i>Cricetulus griseus</i>) and striped hamster (<i>Cricetulus barabensis</i>) are very closely related species with similar karyotypes. The karyotypes differ from each other by one Robertsonian rearrangement and X-chromosome morphology. The level of the tandem repeat (TR) sequences’ evolutional variability is high. The aim of the current work was to trace the TR distribution on the chromosomes of two very closely related species. The striped hamster genome has not yet been sequenced. We classified the Chinese hamster TR in the assemblies available and then compared the mode of the TR distribution in closely related species. Chinese and striped hamsters are separate species due to the relative species specificity of Chinese hamster TR and prominent differences in the TR distribution in both species. The TR variation observed within homologous striped hamster chromosomes is caused by a lack of inbreeding in natural populations. The set of TR tested could be used to examine the CHO lines’ instability that has been observed in heterochromatic regions.https://www.mdpi.com/2227-9059/10/4/925tandem repeatssatellite DNACHO (Chinese hamster ovary cell lines)<i>Cricetulus griseus</i><i>Cricetulus barabensis</i>FISH |
| spellingShingle | Nadezhda G. Ivanova Irina V. Kartavtseva Vera N. Stefanova Dmitrii I. Ostromyshenskii Olga I. Podgornaya Tandem Repeat Diversity in Two Closely Related Hamster Species—The Chinese Hamster (<i>Cricetulus griseus</i>) and Striped Hamster (<i>Cricetulus barabensis</i>) Biomedicines tandem repeats satellite DNA CHO (Chinese hamster ovary cell lines) <i>Cricetulus griseus</i> <i>Cricetulus barabensis</i> FISH |
| title | Tandem Repeat Diversity in Two Closely Related Hamster Species—The Chinese Hamster (<i>Cricetulus griseus</i>) and Striped Hamster (<i>Cricetulus barabensis</i>) |
| title_full | Tandem Repeat Diversity in Two Closely Related Hamster Species—The Chinese Hamster (<i>Cricetulus griseus</i>) and Striped Hamster (<i>Cricetulus barabensis</i>) |
| title_fullStr | Tandem Repeat Diversity in Two Closely Related Hamster Species—The Chinese Hamster (<i>Cricetulus griseus</i>) and Striped Hamster (<i>Cricetulus barabensis</i>) |
| title_full_unstemmed | Tandem Repeat Diversity in Two Closely Related Hamster Species—The Chinese Hamster (<i>Cricetulus griseus</i>) and Striped Hamster (<i>Cricetulus barabensis</i>) |
| title_short | Tandem Repeat Diversity in Two Closely Related Hamster Species—The Chinese Hamster (<i>Cricetulus griseus</i>) and Striped Hamster (<i>Cricetulus barabensis</i>) |
| title_sort | tandem repeat diversity in two closely related hamster species the chinese hamster i cricetulus griseus i and striped hamster i cricetulus barabensis i |
| topic | tandem repeats satellite DNA CHO (Chinese hamster ovary cell lines) <i>Cricetulus griseus</i> <i>Cricetulus barabensis</i> FISH |
| url | https://www.mdpi.com/2227-9059/10/4/925 |
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