Invasive aspergillosis of tympanomastoid cavity

Invasive aspergillosis of the tympanomastoid cavity is an extremely rare clinical incidence in comparison to the invasive fungal infections of the paranasal sinus and other parts of the body. Delay in the diagnosis and treatment of this rare clinical entity often leads to fatal complications such as...

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Main Authors: Santosh Kumar Swain, Priyanka Debta, Ajit Kumar Bishoyi, Rabindranath Padhy
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Journal of the Scientific Society
Subjects:
Online Access:http://www.jscisociety.com/article.asp?issn=0974-5009;year=2019;volume=46;issue=3;spage=106;epage=109;aulast=Swain
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author Santosh Kumar Swain
Priyanka Debta
Ajit Kumar Bishoyi
Rabindranath Padhy
author_facet Santosh Kumar Swain
Priyanka Debta
Ajit Kumar Bishoyi
Rabindranath Padhy
author_sort Santosh Kumar Swain
collection DOAJ
description Invasive aspergillosis of the tympanomastoid cavity is an extremely rare clinical incidence in comparison to the invasive fungal infections of the paranasal sinus and other parts of the body. Delay in the diagnosis and treatment of this rare clinical entity often leads to fatal complications such as skull base osteomyelitis and progressive multiple cranial nerve palsies. The invasive aspergillosis of the tympanomastoid region should be considered as a differential diagnosis for atypical mastoiditis in immunocompromised patients. Here, we report a case of invasive aspergillosis of the tympanomastoid region in a 60-year-old diabetic patient with facial nerve palsy. The diagnosis was done by the demonstration of fungi in the tissue with Gomori methenamine silver staining and confirmed with molecular diagnosis. Surgical debridement of the tympanomastoid region was done along with long-term voriconazole therapy.
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spelling doaj.art-35c0676756a34ac1aa739c2de02e02572022-12-21T20:15:22ZengWolters Kluwer Medknow PublicationsJournal of the Scientific Society0974-50092019-01-0146310610910.4103/jss.JSS_41_19Invasive aspergillosis of tympanomastoid cavitySantosh Kumar SwainPriyanka DebtaAjit Kumar BishoyiRabindranath PadhyInvasive aspergillosis of the tympanomastoid cavity is an extremely rare clinical incidence in comparison to the invasive fungal infections of the paranasal sinus and other parts of the body. Delay in the diagnosis and treatment of this rare clinical entity often leads to fatal complications such as skull base osteomyelitis and progressive multiple cranial nerve palsies. The invasive aspergillosis of the tympanomastoid region should be considered as a differential diagnosis for atypical mastoiditis in immunocompromised patients. Here, we report a case of invasive aspergillosis of the tympanomastoid region in a 60-year-old diabetic patient with facial nerve palsy. The diagnosis was done by the demonstration of fungi in the tissue with Gomori methenamine silver staining and confirmed with molecular diagnosis. Surgical debridement of the tympanomastoid region was done along with long-term voriconazole therapy.http://www.jscisociety.com/article.asp?issn=0974-5009;year=2019;volume=46;issue=3;spage=106;epage=109;aulast=Swaininvasive aspergillosissurgical debridementtympanomastoid cavityvoriconazole
spellingShingle Santosh Kumar Swain
Priyanka Debta
Ajit Kumar Bishoyi
Rabindranath Padhy
Invasive aspergillosis of tympanomastoid cavity
Journal of the Scientific Society
invasive aspergillosis
surgical debridement
tympanomastoid cavity
voriconazole
title Invasive aspergillosis of tympanomastoid cavity
title_full Invasive aspergillosis of tympanomastoid cavity
title_fullStr Invasive aspergillosis of tympanomastoid cavity
title_full_unstemmed Invasive aspergillosis of tympanomastoid cavity
title_short Invasive aspergillosis of tympanomastoid cavity
title_sort invasive aspergillosis of tympanomastoid cavity
topic invasive aspergillosis
surgical debridement
tympanomastoid cavity
voriconazole
url http://www.jscisociety.com/article.asp?issn=0974-5009;year=2019;volume=46;issue=3;spage=106;epage=109;aulast=Swain
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AT priyankadebta invasiveaspergillosisoftympanomastoidcavity
AT ajitkumarbishoyi invasiveaspergillosisoftympanomastoidcavity
AT rabindranathpadhy invasiveaspergillosisoftympanomastoidcavity