Bridging the Translational Gap in Chemotherapy-Induced Peripheral Neuropathy with iPSC-Based Modeling

Bridging the Translational Gap in Chemotherapy-Induced Peripheral Neuropathy with iPSC-Based Modeling

Chemotherapy-induced peripheral neuropathy (CIPN) is a common and potentially serious adverse effect of a wide range of chemotherapeutics. The lack of understanding of the molecular mechanisms underlying CIPN limits the efficacy of chemotherapy and development of therapeutics for treatment and preve...

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Bibliographic Details
Main Authors: Christina Mortensen, Nanna Elman Andersen, Tore Bjerregaard Stage
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cancers
Subjects:
chemotherapy-induced peripheral neuropathy
induced pluripotent stem cells
dorsal root ganglia
sensory neurons
Schwann cells
in vitro cell models
Online Access:https://www.mdpi.com/2072-6694/14/16/3939

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