Host-Guest Interaction of Cucurbit[8]uril with N-(3-Aminopropyl)cyclohexylamine: Cyclohexyl Encapsulation Triggered Ternary Complex
The host-guest interaction of a series of cyclohexyl-appended guests with cucurbit[8]uril (Q[8]) was studied by 1H NMR spectroscopy, isothermal titration calorimetry (ITC), and X-ray crystallography. The X-ray structure revealed that two cycloalkane moieties can be simultaneously encapsulated in the...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-01-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/23/1/175 |
| _version_ | 1819263366282084352 |
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| author | Yu Xia Chuan-Zeng Wang Mengkui Tian Zhu Tao Xin-Long Ni Timothy J. Prior Carl Redshaw |
| author_facet | Yu Xia Chuan-Zeng Wang Mengkui Tian Zhu Tao Xin-Long Ni Timothy J. Prior Carl Redshaw |
| author_sort | Yu Xia |
| collection | DOAJ |
| description | The host-guest interaction of a series of cyclohexyl-appended guests with cucurbit[8]uril (Q[8]) was studied by 1H NMR spectroscopy, isothermal titration calorimetry (ITC), and X-ray crystallography. The X-ray structure revealed that two cycloalkane moieties can be simultaneously encapsulated in the hydrophobic cavity of the Q[8] host to form a ternary complex for the first time. |
| first_indexed | 2024-12-23T20:12:27Z |
| format | Article |
| id | doaj.art-35c682458baf4fa5b29bcff9ab3a6e19 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-23T20:12:27Z |
| publishDate | 2018-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-35c682458baf4fa5b29bcff9ab3a6e192022-12-21T17:32:48ZengMDPI AGMolecules1420-30492018-01-0123117510.3390/molecules23010175molecules23010175Host-Guest Interaction of Cucurbit[8]uril with N-(3-Aminopropyl)cyclohexylamine: Cyclohexyl Encapsulation Triggered Ternary ComplexYu Xia0Chuan-Zeng Wang1Mengkui Tian2Zhu Tao3Xin-Long Ni4Timothy J. Prior5Carl Redshaw6Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Guizhou University, Guiyang 550025, ChinaKey Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Guizhou University, Guiyang 550025, ChinaKey Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Guizhou University, Guiyang 550025, ChinaKey Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Guizhou University, Guiyang 550025, ChinaKey Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Guizhou University, Guiyang 550025, ChinaDepartment of Chemistry, School of Mathematics and Physical Sciences, University of Hull, Hull HU6 7RX, UKDepartment of Chemistry, School of Mathematics and Physical Sciences, University of Hull, Hull HU6 7RX, UKThe host-guest interaction of a series of cyclohexyl-appended guests with cucurbit[8]uril (Q[8]) was studied by 1H NMR spectroscopy, isothermal titration calorimetry (ITC), and X-ray crystallography. The X-ray structure revealed that two cycloalkane moieties can be simultaneously encapsulated in the hydrophobic cavity of the Q[8] host to form a ternary complex for the first time.http://www.mdpi.com/1420-3049/23/1/175cucurbit[8]urilcycloalkane groupshost-guest interactionternary complexX-ray structure |
| spellingShingle | Yu Xia Chuan-Zeng Wang Mengkui Tian Zhu Tao Xin-Long Ni Timothy J. Prior Carl Redshaw Host-Guest Interaction of Cucurbit[8]uril with N-(3-Aminopropyl)cyclohexylamine: Cyclohexyl Encapsulation Triggered Ternary Complex Molecules cucurbit[8]uril cycloalkane groups host-guest interaction ternary complex X-ray structure |
| title | Host-Guest Interaction of Cucurbit[8]uril with N-(3-Aminopropyl)cyclohexylamine: Cyclohexyl Encapsulation Triggered Ternary Complex |
| title_full | Host-Guest Interaction of Cucurbit[8]uril with N-(3-Aminopropyl)cyclohexylamine: Cyclohexyl Encapsulation Triggered Ternary Complex |
| title_fullStr | Host-Guest Interaction of Cucurbit[8]uril with N-(3-Aminopropyl)cyclohexylamine: Cyclohexyl Encapsulation Triggered Ternary Complex |
| title_full_unstemmed | Host-Guest Interaction of Cucurbit[8]uril with N-(3-Aminopropyl)cyclohexylamine: Cyclohexyl Encapsulation Triggered Ternary Complex |
| title_short | Host-Guest Interaction of Cucurbit[8]uril with N-(3-Aminopropyl)cyclohexylamine: Cyclohexyl Encapsulation Triggered Ternary Complex |
| title_sort | host guest interaction of cucurbit 8 uril with n 3 aminopropyl cyclohexylamine cyclohexyl encapsulation triggered ternary complex |
| topic | cucurbit[8]uril cycloalkane groups host-guest interaction ternary complex X-ray structure |
| url | http://www.mdpi.com/1420-3049/23/1/175 |
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