Blainvillea rhomboidea: constituintes químicos e atividade citotóxica Blainvillea rhomboidea: chemical constituents and cytotoxic activity
<abstract language="eng">The phytochemical investigation of the ethanol extract from the aerial parts of Blainvillea rhomboidea (Asteraceae) resulted in the isolation and characterization of 8β-tigloyloxy-grazielia acid, together with the flavonoids derrone, acacetin, luteol...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Química
2010-01-01
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| Series: | Química Nova |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010000500022 |
| _version_ | 1819239554037579776 |
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| author | Regina Ferreira Gomes Hélcio Silva dos Santos Maria Rose Jane R. Albuquerque Otília Deusdênia L. Pessoa Leticia V. Costa Lotufo Claudia do Ó Pessoa Manoel Odorico de Moraes Felipe A. R. Rodrigues |
| author_facet | Regina Ferreira Gomes Hélcio Silva dos Santos Maria Rose Jane R. Albuquerque Otília Deusdênia L. Pessoa Leticia V. Costa Lotufo Claudia do Ó Pessoa Manoel Odorico de Moraes Felipe A. R. Rodrigues |
| author_sort | Regina Ferreira Gomes |
| collection | DOAJ |
| description | <abstract language="eng">The phytochemical investigation of the ethanol extract from the aerial parts of Blainvillea rhomboidea (Asteraceae) resulted in the isolation and characterization of 8β-tigloyloxy-grazielia acid, together with the flavonoids derrone, acacetin, luteolin and luteolin 7-methyl ether, and p-(1-methyl-ethan-1-ol)-phenol. The structures of all compounds were determined by spectroscopic methods (¹H and 13C NMR and HREIMS) and comparison with published spectral data. The flavonoids luteolin and 7-O-metyl-luteolin, isolated from the active dichloromethane fraction, showed moderate cytotoxic activity. |
| first_indexed | 2024-12-23T13:53:58Z |
| format | Article |
| id | doaj.art-35c730a87c314f4889207bec09c55692 |
| institution | Directory Open Access Journal |
| issn | 0100-4042 1678-7064 |
| language | English |
| last_indexed | 2024-12-23T13:53:58Z |
| publishDate | 2010-01-01 |
| publisher | Sociedade Brasileira de Química |
| record_format | Article |
| series | Química Nova |
| spelling | doaj.art-35c730a87c314f4889207bec09c556922022-12-21T17:44:31ZengSociedade Brasileira de QuímicaQuímica Nova0100-40421678-70642010-01-013351122112510.1590/S0100-40422010000500022Blainvillea rhomboidea: constituintes químicos e atividade citotóxica Blainvillea rhomboidea: chemical constituents and cytotoxic activityRegina Ferreira GomesHélcio Silva dos SantosMaria Rose Jane R. AlbuquerqueOtília Deusdênia L. PessoaLeticia V. Costa LotufoClaudia do Ó PessoaManoel Odorico de MoraesFelipe A. R. Rodrigues<abstract language="eng">The phytochemical investigation of the ethanol extract from the aerial parts of Blainvillea rhomboidea (Asteraceae) resulted in the isolation and characterization of 8β-tigloyloxy-grazielia acid, together with the flavonoids derrone, acacetin, luteolin and luteolin 7-methyl ether, and p-(1-methyl-ethan-1-ol)-phenol. The structures of all compounds were determined by spectroscopic methods (¹H and 13C NMR and HREIMS) and comparison with published spectral data. The flavonoids luteolin and 7-O-metyl-luteolin, isolated from the active dichloromethane fraction, showed moderate cytotoxic activity.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010000500022Blainvillea rhomboideaAsteraceaeflavonoids |
| spellingShingle | Regina Ferreira Gomes Hélcio Silva dos Santos Maria Rose Jane R. Albuquerque Otília Deusdênia L. Pessoa Leticia V. Costa Lotufo Claudia do Ó Pessoa Manoel Odorico de Moraes Felipe A. R. Rodrigues Blainvillea rhomboidea: constituintes químicos e atividade citotóxica Blainvillea rhomboidea: chemical constituents and cytotoxic activity Química Nova Blainvillea rhomboidea Asteraceae flavonoids |
| title | Blainvillea rhomboidea: constituintes químicos e atividade citotóxica Blainvillea rhomboidea: chemical constituents and cytotoxic activity |
| title_full | Blainvillea rhomboidea: constituintes químicos e atividade citotóxica Blainvillea rhomboidea: chemical constituents and cytotoxic activity |
| title_fullStr | Blainvillea rhomboidea: constituintes químicos e atividade citotóxica Blainvillea rhomboidea: chemical constituents and cytotoxic activity |
| title_full_unstemmed | Blainvillea rhomboidea: constituintes químicos e atividade citotóxica Blainvillea rhomboidea: chemical constituents and cytotoxic activity |
| title_short | Blainvillea rhomboidea: constituintes químicos e atividade citotóxica Blainvillea rhomboidea: chemical constituents and cytotoxic activity |
| title_sort | blainvillea rhomboidea constituintes quimicos e atividade citotoxica blainvillea rhomboidea chemical constituents and cytotoxic activity |
| topic | Blainvillea rhomboidea Asteraceae flavonoids |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010000500022 |
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