Development of Electrochemiluminecence Sensor for Verapamil Hydrochloride Based on TiO2 sol/ZnO@Ag/Silica sol-Ru(bpy)32+ Modified Pyrolytic Graphite Electrode
A sensitive solid-state electrochemiluminesence (ECL) sensor for verapamil hydrochloride (VpCl) was fabricated based on the film formability of TiO2 sol and electrocatalysis of ZnO@Ag. The immobilization of tris(2, 2′-bipyridine) ruthenium (II) (Ru(bpy)32+) by using TiO2 sol/ZnO@Ag/silica sol compos...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Electrochemical Society of Japan
2022-07-01
|
| Series: | Electrochemistry |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/electrochemistry/90/7/90_22-00042/_html/-char/en |
| _version_ | 1797964453229101056 |
|---|---|
| author | Ying LUO Yingshi HUANG Yanqing LI Jun FENG |
| author_facet | Ying LUO Yingshi HUANG Yanqing LI Jun FENG |
| author_sort | Ying LUO |
| collection | DOAJ |
| description | A sensitive solid-state electrochemiluminesence (ECL) sensor for verapamil hydrochloride (VpCl) was fabricated based on the film formability of TiO2 sol and electrocatalysis of ZnO@Ag. The immobilization of tris(2, 2′-bipyridine) ruthenium (II) (Ru(bpy)32+) by using TiO2 sol/ZnO@Ag/silica sol composite exhibited stable ECL behaviors, and a sensitive and selective method was developed for VpCl determination. Under the optimal conditions, the ECL response of the sensor showed a linear correlation to the concentration of VpCl in the range of 1.0 × 10−7–1.0 × 10−4 mol L−1 (R2 = 0.9832) with a detection limit of 7.00 × 10−9 mol L−1 (S/N = 3). The RSD of ECL response was 2.07 % for 1.0 × 10−5 mol L−1 VpCl under 10 continuous cyclic scans. The spiked recovery was 97.90–104.50 % for determination of real VpCl sample. The proposed method exhibited selectivity and sensitivity for VpCl, and improved efficiency of Ru(bpy)32+. |
| first_indexed | 2024-04-11T01:44:15Z |
| format | Article |
| id | doaj.art-35ca38d680524cb0a8b58e410a99486d |
| institution | Directory Open Access Journal |
| issn | 2186-2451 |
| language | English |
| last_indexed | 2024-04-11T01:44:15Z |
| publishDate | 2022-07-01 |
| publisher | The Electrochemical Society of Japan |
| record_format | Article |
| series | Electrochemistry |
| spelling | doaj.art-35ca38d680524cb0a8b58e410a99486d2023-01-03T07:56:31ZengThe Electrochemical Society of JapanElectrochemistry2186-24512022-07-0190707700507700510.5796/electrochemistry.22-00042electrochemistryDevelopment of Electrochemiluminecence Sensor for Verapamil Hydrochloride Based on TiO2 sol/ZnO@Ag/Silica sol-Ru(bpy)32+ Modified Pyrolytic Graphite ElectrodeYing LUO0Yingshi HUANG1Yanqing LI2Jun FENG3School of Food and Chemical Engineering, Liuzhou Institute and TechnologyLibrary, Shanghai University of Engineering ScienceCollege of Biological and Chemical Engineering, Guangxi University of Science and TechnologyCollege of Biological and Chemical Engineering, Guangxi University of Science and TechnologyA sensitive solid-state electrochemiluminesence (ECL) sensor for verapamil hydrochloride (VpCl) was fabricated based on the film formability of TiO2 sol and electrocatalysis of ZnO@Ag. The immobilization of tris(2, 2′-bipyridine) ruthenium (II) (Ru(bpy)32+) by using TiO2 sol/ZnO@Ag/silica sol composite exhibited stable ECL behaviors, and a sensitive and selective method was developed for VpCl determination. Under the optimal conditions, the ECL response of the sensor showed a linear correlation to the concentration of VpCl in the range of 1.0 × 10−7–1.0 × 10−4 mol L−1 (R2 = 0.9832) with a detection limit of 7.00 × 10−9 mol L−1 (S/N = 3). The RSD of ECL response was 2.07 % for 1.0 × 10−5 mol L−1 VpCl under 10 continuous cyclic scans. The spiked recovery was 97.90–104.50 % for determination of real VpCl sample. The proposed method exhibited selectivity and sensitivity for VpCl, and improved efficiency of Ru(bpy)32+.https://www.jstage.jst.go.jp/article/electrochemistry/90/7/90_22-00042/_html/-char/enelectrochemiluminesencezno@agru(bpy)32+verapamil hydrochloride |
| spellingShingle | Ying LUO Yingshi HUANG Yanqing LI Jun FENG Development of Electrochemiluminecence Sensor for Verapamil Hydrochloride Based on TiO2 sol/ZnO@Ag/Silica sol-Ru(bpy)32+ Modified Pyrolytic Graphite Electrode Electrochemistry electrochemiluminesence zno@ag ru(bpy)32+ verapamil hydrochloride |
| title | Development of Electrochemiluminecence Sensor for Verapamil Hydrochloride Based on TiO2 sol/ZnO@Ag/Silica sol-Ru(bpy)32+ Modified Pyrolytic Graphite Electrode |
| title_full | Development of Electrochemiluminecence Sensor for Verapamil Hydrochloride Based on TiO2 sol/ZnO@Ag/Silica sol-Ru(bpy)32+ Modified Pyrolytic Graphite Electrode |
| title_fullStr | Development of Electrochemiluminecence Sensor for Verapamil Hydrochloride Based on TiO2 sol/ZnO@Ag/Silica sol-Ru(bpy)32+ Modified Pyrolytic Graphite Electrode |
| title_full_unstemmed | Development of Electrochemiluminecence Sensor for Verapamil Hydrochloride Based on TiO2 sol/ZnO@Ag/Silica sol-Ru(bpy)32+ Modified Pyrolytic Graphite Electrode |
| title_short | Development of Electrochemiluminecence Sensor for Verapamil Hydrochloride Based on TiO2 sol/ZnO@Ag/Silica sol-Ru(bpy)32+ Modified Pyrolytic Graphite Electrode |
| title_sort | development of electrochemiluminecence sensor for verapamil hydrochloride based on tio2 sol zno ag silica sol ru bpy 32 modified pyrolytic graphite electrode |
| topic | electrochemiluminesence zno@ag ru(bpy)32+ verapamil hydrochloride |
| url | https://www.jstage.jst.go.jp/article/electrochemistry/90/7/90_22-00042/_html/-char/en |
| work_keys_str_mv | AT yingluo developmentofelectrochemiluminecencesensorforverapamilhydrochloridebasedontio2solznoagsilicasolrubpy32modifiedpyrolyticgraphiteelectrode AT yingshihuang developmentofelectrochemiluminecencesensorforverapamilhydrochloridebasedontio2solznoagsilicasolrubpy32modifiedpyrolyticgraphiteelectrode AT yanqingli developmentofelectrochemiluminecencesensorforverapamilhydrochloridebasedontio2solznoagsilicasolrubpy32modifiedpyrolyticgraphiteelectrode AT junfeng developmentofelectrochemiluminecencesensorforverapamilhydrochloridebasedontio2solznoagsilicasolrubpy32modifiedpyrolyticgraphiteelectrode |