NAP1L1: A Novel Human Colorectal Cancer Biomarker Derived From Animal Models of Apc Inactivation

NAP1L1: A Novel Human Colorectal Cancer Biomarker Derived From Animal Models of Apc Inactivation

IntroductionColorectal cancer (CRC) is the second leading cause of cancer death worldwide and most deaths result from metastases. We have analyzed animal models in which Apc, a gene that is frequently mutated during the early stages of colorectal carcinogenesis, was inactivated and human samples to...

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Bibliographic Details
Main Authors: Cleberson J. S. Queiroz, Fei Song, Karen R. Reed, Nadeem Al-Khafaji, Alan R. Clarke, Dale Vimalachandran, Fabio Miyajima, D. Mark Pritchard, John R. Jenkins
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
biomarkers
Apc
NAP1L1
prognosis
survival
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01565/full

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