Dao-Chi Powder Ameliorates Pancreatitis-Induced Intestinal and Cardiac Injuries via Regulating the Nrf2-HO-1-HMGB1 Signaling Pathway in Rats

Dao-Chi Powder Ameliorates Pancreatitis-Induced Intestinal and Cardiac Injuries via Regulating the Nrf2-HO-1-HMGB1 Signaling Pathway in Rats

Dao-Chi powder (DCP) has been widely used in the treatment of inflammatory diseases in the clinical practice of traditional Chinese medicine, but has not been used in acute pancreatitis (AP). This study aimed to evaluate the effect of DCP on severe AP (SAP) and SAP-associated intestinal and cardiac...

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Bibliographic Details
Main Authors: Jiaqi Yao, Yifan Miao, Yumei Zhang, Lv Zhu, Huan Chen, Xiajia Wu, Yue Yang, Xiaoyu Dai, Qian Hu, Meihua Wan, Wenfu Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
severe acute pancreatitis
Dao-Chi powder
oxidative stress
inflammatory responses
Nrf2/HO-1/HMGB1
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.922130/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.922130/full

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