The telomere binding protein TRF2 induces chromatin compaction.

Mammalian telomeres are specialized chromatin structures that require the telomere binding protein, TRF2, for maintaining chromosome stability. In addition to its ability to modulate DNA repair activities, TRF2 also has direct effects on DNA structure and topology. Given that mammalian telomeric chr...

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Bibliographic Details
Main Authors: Asmaa M Baker, Qiang Fu, William Hayward, Samuel Victoria, Ilene M Pedroso, Stuart M Lindsay, Terace M Fletcher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3079743?pdf=render