Eggmanone Effectively Overcomes Prostate Cancer Cell Chemoresistance

Eggmanone Effectively Overcomes Prostate Cancer Cell Chemoresistance

Prostate cancer chemoresistance is a major therapeutic problem, and the underlying mechanism is not well understood and effective therapies to overcome this problem are not available. Phosphodiesterase-4 (PDE4), a main intracellular enzyme for cAMP hydrolysis, has been previously shown to involve in...

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Bibliographic Details
Main Authors: Chen Xie, Pen-Jen Lin, Jijun Hao
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biomedicines
Subjects:
chemoresistance
prostate cancer
Phosphodiesterase-4
cancer stem cells
Eggmanone
Online Access:https://www.mdpi.com/2227-9059/9/5/538

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