Computational Simulation of Exosome Transport in Tumor Microenvironment

Computational Simulation of Exosome Transport in Tumor Microenvironment

Cellular exosome-mediated crosstalk in tumor microenvironment (TME) is a critical component of anti-tumor immune responses. In addition to particle size, exosome transport and uptake by target cells is influenced by physical and physiological factors, including interstitial fluid pressure, and exoso...

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Bibliographic Details
Main Authors: Roy Koomullil, Behnam Tehrani, Kayla Goliwas, Yong Wang, Selvarangan Ponnazhagan, Joel Berry, Jessy Deshane
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Medicine
Subjects:
exosome
interstitial fluid flow
diffusion
computational modeling
transport equations
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.643793/full

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