Trends in the Care of Diabetic Macular Edema: Analysis of a National Cohort.
PURPOSE:To evaluate how the monitoring and treatment for diabetic macular edema (DME) has changed in a national sample. DESIGN:Retrospective cohort study. METHODS: SETTING:Administrative medical claims data from a large, national U.S. insurer. STUDY POPULATION:Beneficiaries of a U.S. insurance compa...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2016-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4765886?pdf=render |
| _version_ | 1818760179927220224 |
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| author | Brian L VanderBeek Neepa Shah Purak C Parikh Liyuan Ma |
| author_facet | Brian L VanderBeek Neepa Shah Purak C Parikh Liyuan Ma |
| author_sort | Brian L VanderBeek |
| collection | DOAJ |
| description | PURPOSE:To evaluate how the monitoring and treatment for diabetic macular edema (DME) has changed in a national sample. DESIGN:Retrospective cohort study. METHODS: SETTING:Administrative medical claims data from a large, national U.S. insurer. STUDY POPULATION:Beneficiaries of a U.S. insurance company. OBSERVATION PROCEDURES:All incident cases of DME were found. Those in years 2002/3, 2006 and 2010 were followed for a 2-year observation period and those from 2009, 2010 and 2011 for a 1-year observation period. MAIN OUTCOME MEASURES:Types and frequencies of treatment were tallied and compared over each of the cohorts. RESULTS:Two-year cohorts had 233, 251 and 756 patients in 2002/3, 2006 and 2010 respectively. One-year cohorts had 1002, 1119 and 1382 patients in 2009, 2010 and 2011, respectively. Both percentage of patients receiving therapy and number of treatments given increased across the 2-year cohorts for both focal laser and anti-vascular endothelial growth factor (anti-VEGF) (p<0.001). The highest use of anti-VEGF agents in any of the cohorts was in the 2011 1-year group that only averaged 3.78 injections. Focal laser was used 2.5x as frequently as anti-VEGF injections in the most recent cohorts with only a high of 14.0% of DME patients receiving anti-VEGF therapy in any of the cohorts. CONCLUSION:Regardless of treatment modality (laser or injection) DME patients received vastly fewer treatments than patients in randomized control trials. Despite the proven superior visual outcomes of anti-VEGF agents over focal laser in DME, focal laser was still used more frequently. |
| first_indexed | 2024-12-18T06:54:31Z |
| format | Article |
| id | doaj.art-35d992f2a2c24495b3fdfc9d394d33e1 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-18T06:54:31Z |
| publishDate | 2016-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-35d992f2a2c24495b3fdfc9d394d33e12022-12-21T21:17:13ZengPublic Library of Science (PLoS)PLoS ONE1932-62032016-01-01112e014945010.1371/journal.pone.0149450Trends in the Care of Diabetic Macular Edema: Analysis of a National Cohort.Brian L VanderBeekNeepa ShahPurak C ParikhLiyuan MaPURPOSE:To evaluate how the monitoring and treatment for diabetic macular edema (DME) has changed in a national sample. DESIGN:Retrospective cohort study. METHODS: SETTING:Administrative medical claims data from a large, national U.S. insurer. STUDY POPULATION:Beneficiaries of a U.S. insurance company. OBSERVATION PROCEDURES:All incident cases of DME were found. Those in years 2002/3, 2006 and 2010 were followed for a 2-year observation period and those from 2009, 2010 and 2011 for a 1-year observation period. MAIN OUTCOME MEASURES:Types and frequencies of treatment were tallied and compared over each of the cohorts. RESULTS:Two-year cohorts had 233, 251 and 756 patients in 2002/3, 2006 and 2010 respectively. One-year cohorts had 1002, 1119 and 1382 patients in 2009, 2010 and 2011, respectively. Both percentage of patients receiving therapy and number of treatments given increased across the 2-year cohorts for both focal laser and anti-vascular endothelial growth factor (anti-VEGF) (p<0.001). The highest use of anti-VEGF agents in any of the cohorts was in the 2011 1-year group that only averaged 3.78 injections. Focal laser was used 2.5x as frequently as anti-VEGF injections in the most recent cohorts with only a high of 14.0% of DME patients receiving anti-VEGF therapy in any of the cohorts. CONCLUSION:Regardless of treatment modality (laser or injection) DME patients received vastly fewer treatments than patients in randomized control trials. Despite the proven superior visual outcomes of anti-VEGF agents over focal laser in DME, focal laser was still used more frequently.http://europepmc.org/articles/PMC4765886?pdf=render |
| spellingShingle | Brian L VanderBeek Neepa Shah Purak C Parikh Liyuan Ma Trends in the Care of Diabetic Macular Edema: Analysis of a National Cohort. PLoS ONE |
| title | Trends in the Care of Diabetic Macular Edema: Analysis of a National Cohort. |
| title_full | Trends in the Care of Diabetic Macular Edema: Analysis of a National Cohort. |
| title_fullStr | Trends in the Care of Diabetic Macular Edema: Analysis of a National Cohort. |
| title_full_unstemmed | Trends in the Care of Diabetic Macular Edema: Analysis of a National Cohort. |
| title_short | Trends in the Care of Diabetic Macular Edema: Analysis of a National Cohort. |
| title_sort | trends in the care of diabetic macular edema analysis of a national cohort |
| url | http://europepmc.org/articles/PMC4765886?pdf=render |
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