Oral Alitretinoin for the Treatment of Recalcitrant Pityriasis Rubra Pilaris

Treatment of pityriasis rubra pilaris is still challenging. We here present a 74-year-old woman who had not experienced stable remission of her skin symptoms during prior treatments including topical and systemic corticosteroids, phototherapy, orally administered acitretin, cyclosporine, methotrexat...

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Main Authors: Laurenz Schmitt, Oliver Inhoff, Edgar Dippel
Format: Article
Language:English
Published: Karger Publishers 2011-04-01
Series:Case Reports in Dermatology
Subjects:
Online Access:http://www.karger.com/Article/FullText/327704
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author Laurenz Schmitt
Oliver Inhoff
Edgar Dippel
author_facet Laurenz Schmitt
Oliver Inhoff
Edgar Dippel
author_sort Laurenz Schmitt
collection DOAJ
description Treatment of pityriasis rubra pilaris is still challenging. We here present a 74-year-old woman who had not experienced stable remission of her skin symptoms during prior treatments including topical and systemic corticosteroids, phototherapy, orally administered acitretin, cyclosporine, methotrexate and adalimumab. A therapy with oral alitretinoin was started and tolerated very well. After a few weeks, skin condition improved significantly and itching and scaling disappeared. The present case shows that alitretinoin might be an alternative in the treatment of recalcitrant pityriasis rubra pilaris type I. Further studies are needed to investigate the benefit of this encouraging result.
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spelling doaj.art-35da818f129544ad853f71f16ec334a92022-12-22T02:35:36ZengKarger PublishersCase Reports in Dermatology1662-65672011-04-0131858810.1159/000327704327704Oral Alitretinoin for the Treatment of Recalcitrant Pityriasis Rubra PilarisLaurenz SchmittOliver InhoffEdgar DippelTreatment of pityriasis rubra pilaris is still challenging. We here present a 74-year-old woman who had not experienced stable remission of her skin symptoms during prior treatments including topical and systemic corticosteroids, phototherapy, orally administered acitretin, cyclosporine, methotrexate and adalimumab. A therapy with oral alitretinoin was started and tolerated very well. After a few weeks, skin condition improved significantly and itching and scaling disappeared. The present case shows that alitretinoin might be an alternative in the treatment of recalcitrant pityriasis rubra pilaris type I. Further studies are needed to investigate the benefit of this encouraging result.http://www.karger.com/Article/FullText/327704Hair lossRetonoids
spellingShingle Laurenz Schmitt
Oliver Inhoff
Edgar Dippel
Oral Alitretinoin for the Treatment of Recalcitrant Pityriasis Rubra Pilaris
Case Reports in Dermatology
Hair loss
Retonoids
title Oral Alitretinoin for the Treatment of Recalcitrant Pityriasis Rubra Pilaris
title_full Oral Alitretinoin for the Treatment of Recalcitrant Pityriasis Rubra Pilaris
title_fullStr Oral Alitretinoin for the Treatment of Recalcitrant Pityriasis Rubra Pilaris
title_full_unstemmed Oral Alitretinoin for the Treatment of Recalcitrant Pityriasis Rubra Pilaris
title_short Oral Alitretinoin for the Treatment of Recalcitrant Pityriasis Rubra Pilaris
title_sort oral alitretinoin for the treatment of recalcitrant pityriasis rubra pilaris
topic Hair loss
Retonoids
url http://www.karger.com/Article/FullText/327704
work_keys_str_mv AT laurenzschmitt oralalitretinoinforthetreatmentofrecalcitrantpityriasisrubrapilaris
AT oliverinhoff oralalitretinoinforthetreatmentofrecalcitrantpityriasisrubrapilaris
AT edgardippel oralalitretinoinforthetreatmentofrecalcitrantpityriasisrubrapilaris