Comprehensive mismatch repair gene panel identifies variants in patients with Lynch‐like syndrome

Comprehensive mismatch repair gene panel identifies variants in patients with Lynch‐like syndrome

Abstract Background Lynch‐like syndrome (LLS) represents around 50% of the patients fulfilling the Amsterdam Criteria II/revised Bethesda Guidelines, characterized by a strong family history of Lynch Syndrome (LS) associated cancer, where a causative variant was not identified during genetic testing...

Full description

Bibliographic Details
Main Authors: Alexandre Xavier, Maren Fridtjofsen Olsen, Liss A. Lavik, Jostein Johansen, Ashish Kumar Singh, Wenche Sjursen, Rodney J. Scott, Bente A. Talseth‐Palmer
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
Genetics
germline mutation
high‐throughput sequencing
Lynch syndrome
MMR gene panel
Online Access:https://doi.org/10.1002/mgg3.850

Similar Items

Similar Items