Lentiviral transduction of Tar Decoy and CCR5 ribozyme into CD34+ progenitor cells and derivation of HIV-1 resistant T cells and macrophages
<p>Abstract</p> <p>Background</p> <p>RNA based antiviral approaches against HIV-1 are among the most promising for long-term gene therapy. These include ribozymes, aptamers (decoys), and small interfering RNAs (siRNAs). Lentiviral vectors are ideal for transduction of s...
Main Authors: | Rossi John, Remling Leila, Li Ming-Jie, Banerjea Akhil, Akkina Ramesh |
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Format: | Article |
Language: | English |
Published: |
BMC
2004-12-01
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Series: | AIDS Research and Therapy |
Subjects: | |
Online Access: | http://www.aidsrestherapy.com/content/1/1/2 |
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