Parotid Gland Primary Amelanotic Malignant Melanoma

Amelanotic malignant melanoma (AMM) represents only 2%–8% of all malignant melanomas, and primary AMM of the parotid gland is very rarely diagnosed. This is the second case of primary AMM of the parotid gland in the literature. The aim of this report is to discuss our case and this rare entity. The...

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Main Authors: Eltaf Ayça Özbal Koç, Çiğdem Kalaycık Ertugay, Şemsi Altaner
Format: Article
Language:English
Published: Galenos Yayinevi 2016-12-01
Series:İstanbul Medical Journal
Subjects:
Online Access: http://imj.galenos.com.tr/archives/archive-detail/article-preview/parotid-gland-primary-amelanotic-malignant-melanom/20816
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author Eltaf Ayça Özbal Koç
Çiğdem Kalaycık Ertugay
Şemsi Altaner
author_facet Eltaf Ayça Özbal Koç
Çiğdem Kalaycık Ertugay
Şemsi Altaner
author_sort Eltaf Ayça Özbal Koç
collection DOAJ
description Amelanotic malignant melanoma (AMM) represents only 2%–8% of all malignant melanomas, and primary AMM of the parotid gland is very rarely diagnosed. This is the second case of primary AMM of the parotid gland in the literature. The aim of this report is to discuss our case and this rare entity. The detection of AMM is very complex because the pathology results can be confused with those for inflammatory processes and benign and malignant tumors. Immunohistochemical analysis of S100 protein and human melanoma black 45 (HMB45) analysis provides guidance in the differential diagnosis of AMM. In this report, we present a rapidly growing amelanotic malignant melanoma in the parotid gland. Examination of the patient and radiological studies showed no other lesions.
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spelling doaj.art-35e514f907904379ada82019ca4b4a552023-02-15T16:08:20ZengGalenos Yayineviİstanbul Medical Journal2619-97932148-094X2016-12-0117414714910.5152/imj.2016.7905813049054Parotid Gland Primary Amelanotic Malignant MelanomaEltaf Ayça Özbal Koç0Çiğdem Kalaycık Ertugay1Şemsi Altaner2 Department of Otorhinolaryngology, Başkent University İstanbul Hospital, İstanbul, Türkiye Clinic of Otorhinolaryngology, Haydarpaşa Numune Training and Research Hospital, İstanbul, Türkiye Department of Pathology, Başkent University İstanbul Hospital, İstanbul, Türkiye Amelanotic malignant melanoma (AMM) represents only 2%–8% of all malignant melanomas, and primary AMM of the parotid gland is very rarely diagnosed. This is the second case of primary AMM of the parotid gland in the literature. The aim of this report is to discuss our case and this rare entity. The detection of AMM is very complex because the pathology results can be confused with those for inflammatory processes and benign and malignant tumors. Immunohistochemical analysis of S100 protein and human melanoma black 45 (HMB45) analysis provides guidance in the differential diagnosis of AMM. In this report, we present a rapidly growing amelanotic malignant melanoma in the parotid gland. Examination of the patient and radiological studies showed no other lesions. http://imj.galenos.com.tr/archives/archive-detail/article-preview/parotid-gland-primary-amelanotic-malignant-melanom/20816 Melanomaparotid glandtumor
spellingShingle Eltaf Ayça Özbal Koç
Çiğdem Kalaycık Ertugay
Şemsi Altaner
Parotid Gland Primary Amelanotic Malignant Melanoma
İstanbul Medical Journal
Melanoma
parotid gland
tumor
title Parotid Gland Primary Amelanotic Malignant Melanoma
title_full Parotid Gland Primary Amelanotic Malignant Melanoma
title_fullStr Parotid Gland Primary Amelanotic Malignant Melanoma
title_full_unstemmed Parotid Gland Primary Amelanotic Malignant Melanoma
title_short Parotid Gland Primary Amelanotic Malignant Melanoma
title_sort parotid gland primary amelanotic malignant melanoma
topic Melanoma
parotid gland
tumor
url http://imj.galenos.com.tr/archives/archive-detail/article-preview/parotid-gland-primary-amelanotic-malignant-melanom/20816
work_keys_str_mv AT eltafaycaozbalkoc parotidglandprimaryamelanoticmalignantmelanoma
AT cigdemkalaycıkertugay parotidglandprimaryamelanoticmalignantmelanoma
AT semsialtaner parotidglandprimaryamelanoticmalignantmelanoma