Post Banding Ulcer Haemorrhage: a Contributor to Morality in Patients with Liver Cirrhosis
Objectives: To evaluate the frequency, risk factors and mortality of post-banding bleeding in cirrhosis. Study Design: Retrospective longitudinal Study. Place and Duration of Study: Department of Medicine, Fauji Foundation Hospital, Rawalpindi Pakistan, from Feb to Jul 2021. Methodology: Esop...
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| Format: | Article |
| Language: | English |
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Army Medical College Rawalpindi
2023-12-01
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| Series: | Pakistan Armed Forces Medical Journal |
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| Online Access: | https://www.pafmj.org/PAFMJ/article/view/8835 |
| _version_ | 1797341000830550016 |
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| author | Shahida Perveen Omar Ahsan Batool Butt Atif Abbas Sehrish Jahan Asif Syeda Fatima Hassan |
| author_facet | Shahida Perveen Omar Ahsan Batool Butt Atif Abbas Sehrish Jahan Asif Syeda Fatima Hassan |
| author_sort | Shahida Perveen |
| collection | DOAJ |
| description |
Objectives: To evaluate the frequency, risk factors and mortality of post-banding bleeding in cirrhosis.
Study Design: Retrospective longitudinal Study.
Place and Duration of Study: Department of Medicine, Fauji Foundation Hospital, Rawalpindi Pakistan, from Feb to Jul 2021.
Methodology: Esophageal variceal band ligation (EVBL) was done in 123 patients. The study cohort was divided into two
groups: Group-1 without re-bleed and Group-2 with re-bleed. Blood chemistry, Child-Pugh and MELD score, including the
indications of EVBL and risk factors, were also analysed. Regression analysis was performed.
Results: Re-bleed occurred in 10.6% (n=13) of patients. The mean duration between ligation and re-bleed was 8.75±2.8 days. Oesophageal ulcers were the most common cause of re-bleeding (38.5%). Mortality rates among the two groups were 21.8 %( n=24) and 30.8 %( n=4), respectively. The model for end-stage liver disease score (OR 2.177, CI 1.069-4.43, p .03), APTT (OR 0.593, CI 0.397-0.887, p .01) and Sodium (OR 1.345, CI 1.07-1.69, p<0.01) were detected as the predictors of re-bleed.
Conclusion: Although re-bleeding after banding occurs in a trivial number of patients, it contributes to mortality.
Coagulopathy, high sodium and MELD score are major predictors.
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| first_indexed | 2024-03-08T10:11:33Z |
| format | Article |
| id | doaj.art-35e72aefb2024ca3897277033b4e1259 |
| institution | Directory Open Access Journal |
| issn | 0030-9648 2411-8842 |
| language | English |
| last_indexed | 2024-03-08T10:11:33Z |
| publishDate | 2023-12-01 |
| publisher | Army Medical College Rawalpindi |
| record_format | Article |
| series | Pakistan Armed Forces Medical Journal |
| spelling | doaj.art-35e72aefb2024ca3897277033b4e12592024-01-29T08:22:37ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422023-12-0173610.51253/pafmj.v73i6.8835Post Banding Ulcer Haemorrhage: a Contributor to Morality in Patients with Liver CirrhosisShahida Perveen0Omar Ahsan1Batool Butt2Atif Abbas3Sehrish Jahan Asif4Syeda Fatima Hassan5Department of Medicine, Foundation University School of Health Sciences (FUSH), Islamabad PakistanDepartment of Medicine, Foundation University School of Health Sciences (FUSH), Islamabad PakistanDepartment of Medicine, Foundation University School of Health Sciences (FUSH), Islamabad PakistanDepartment of Medicine, Fauji Foundation Hospital, Rawalpindi PakistanDepartment of Medicine, Fauji Foundation Hospital, Rawalpindi PakistanDepartment of Pulmonology, Shaafi International Hospital, Islamabad Objectives: To evaluate the frequency, risk factors and mortality of post-banding bleeding in cirrhosis. Study Design: Retrospective longitudinal Study. Place and Duration of Study: Department of Medicine, Fauji Foundation Hospital, Rawalpindi Pakistan, from Feb to Jul 2021. Methodology: Esophageal variceal band ligation (EVBL) was done in 123 patients. The study cohort was divided into two groups: Group-1 without re-bleed and Group-2 with re-bleed. Blood chemistry, Child-Pugh and MELD score, including the indications of EVBL and risk factors, were also analysed. Regression analysis was performed. Results: Re-bleed occurred in 10.6% (n=13) of patients. The mean duration between ligation and re-bleed was 8.75±2.8 days. Oesophageal ulcers were the most common cause of re-bleeding (38.5%). Mortality rates among the two groups were 21.8 %( n=24) and 30.8 %( n=4), respectively. The model for end-stage liver disease score (OR 2.177, CI 1.069-4.43, p .03), APTT (OR 0.593, CI 0.397-0.887, p .01) and Sodium (OR 1.345, CI 1.07-1.69, p<0.01) were detected as the predictors of re-bleed. Conclusion: Although re-bleeding after banding occurs in a trivial number of patients, it contributes to mortality. Coagulopathy, high sodium and MELD score are major predictors. https://www.pafmj.org/PAFMJ/article/view/8835EndoscopyEndoscopic variceal band ligation (EVBL)Model for end-stage liver disease scorePost banding ulcer haemorrhage |
| spellingShingle | Shahida Perveen Omar Ahsan Batool Butt Atif Abbas Sehrish Jahan Asif Syeda Fatima Hassan Post Banding Ulcer Haemorrhage: a Contributor to Morality in Patients with Liver Cirrhosis Pakistan Armed Forces Medical Journal Endoscopy Endoscopic variceal band ligation (EVBL) Model for end-stage liver disease score Post banding ulcer haemorrhage |
| title | Post Banding Ulcer Haemorrhage: a Contributor to Morality in Patients with Liver Cirrhosis |
| title_full | Post Banding Ulcer Haemorrhage: a Contributor to Morality in Patients with Liver Cirrhosis |
| title_fullStr | Post Banding Ulcer Haemorrhage: a Contributor to Morality in Patients with Liver Cirrhosis |
| title_full_unstemmed | Post Banding Ulcer Haemorrhage: a Contributor to Morality in Patients with Liver Cirrhosis |
| title_short | Post Banding Ulcer Haemorrhage: a Contributor to Morality in Patients with Liver Cirrhosis |
| title_sort | post banding ulcer haemorrhage a contributor to morality in patients with liver cirrhosis |
| topic | Endoscopy Endoscopic variceal band ligation (EVBL) Model for end-stage liver disease score Post banding ulcer haemorrhage |
| url | https://www.pafmj.org/PAFMJ/article/view/8835 |
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