Hyperuricemia remodels the serum proteome toward a higher inflammatory state

Hyperuricemia remodels the serum proteome toward a higher inflammatory state

Summary: Gout is an autoinflammatory disease triggered by a complex innate immune response to MSU crystals and inflammatory triggers. While hyperuricemia is an obligatory risk factor for the development of gout, the majority of individuals with hyperuricemia never develop gout but have an increased...

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Bibliographic Details
Main Authors: Georgiana Cabău, Orsolya Gaal, Medeea Badii, Valentin Nica, Andreea-Manuela Mirea, Ioana Hotea, Cristina Pamfil, Radu A. Popp, Mihai G. Netea, Simona Rednic, Tania O. Crișan, Leo A.B. Joosten
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Disease
Health sciences
Proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223019867

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