Casein kinase 2 phosphorylates and induces the SALL2 tumor suppressor degradation in colon cancer cells

Casein kinase 2 phosphorylates and induces the SALL2 tumor suppressor degradation in colon cancer cells

Abstract Spalt-like proteins are Zinc finger transcription factors from Caenorhabditis elegans to vertebrates, with critical roles in development. In vertebrates, four paralogues have been identified (SALL1-4), and SALL2 is the family’s most dissimilar member. SALL2 is required during brain and eye...

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Main Authors: V. E. Hermosilla, L. Gyenis, A. J. Rabalski, M. E. Armijo, P. Sepúlveda, F. Duprat, D. Benítez-Riquelme, F. Fuentes-Villalobos, A. Quiroz, M. I. Hepp, C. Farkas, M. Mastel, I. González-Chavarría, R. Jackstadt, D. W. Litchfield, A. F. Castro, R. Pincheira
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06591-z

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https://doi.org/10.1038/s41419-024-06591-z

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