Morphology, microbiota, and metabolome along the intestinal tract of female turkeys
ABSTRACT: The global turkey industry is confronted with emerging challenges regarding health and welfare. Performance and disease resilience are directly linked to gut health. A clear definition of a healthy gut is a prerequisite to developing new strategies for improved gut health and, thus, genera...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-11-01
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| Series: | Poultry Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0032579122003376 |
| _version_ | 1797991471418179584 |
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| author | Janina Rzeznitzeck Frederic J. Hoerr Ivan Rychlik Karen Methling Michael Lalk Alexandra Rath Alexandra von Altrock Silke Rautenschlein |
| author_facet | Janina Rzeznitzeck Frederic J. Hoerr Ivan Rychlik Karen Methling Michael Lalk Alexandra Rath Alexandra von Altrock Silke Rautenschlein |
| author_sort | Janina Rzeznitzeck |
| collection | DOAJ |
| description | ABSTRACT: The global turkey industry is confronted with emerging challenges regarding health and welfare. Performance and disease resilience are directly linked to gut health. A clear definition of a healthy gut is a prerequisite to developing new strategies for improved gut health and, thus, general health, welfare and productivity. To date, detailed knowledge about gut health characteristics, especially during the critical fattening period, is still lacking for turkeys. Therefore, the goal of this study was to describe the morphology, microbiota, and metabolome along the intestinal tract of clinically healthy Salmonella- and Campylobacter-free commercial turkey hens throughout the fattening period from 7 to 10 wk posthatch, and obtain information on the stability of the investigated values over time. Feed changes were avoided directly preceding and during the investigation period. Investigation methods included histomorphometric measurement of intestinal villi and crypts, Illumina-sequencing for microbiota analysis, and proton nuclear magnetic resonance spectroscopy for metabolite identification and quantification. Overall, the study demonstrated a high repeatability across all 3 experiments and gut section differences observed coincided with their functions. It was demonstrated that gut maturation, defined by gut microbiota stability, is reached earlier in the ceca than any other intestinal section where morphological changes are ongoing throughout the fattening period. Therefore, the present study provides valuable information necessary to advise future studies on the development and implementation of measures to support gut maturation and establish a protective microbiota in commercial turkeys. |
| first_indexed | 2024-04-11T08:51:41Z |
| format | Article |
| id | doaj.art-35ef3b87e8da43668af9e3d4fe9dbfbc |
| institution | Directory Open Access Journal |
| issn | 0032-5791 |
| language | English |
| last_indexed | 2024-04-11T08:51:41Z |
| publishDate | 2022-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Poultry Science |
| spelling | doaj.art-35ef3b87e8da43668af9e3d4fe9dbfbc2022-12-22T04:33:27ZengElsevierPoultry Science0032-57912022-11-0110111102046Morphology, microbiota, and metabolome along the intestinal tract of female turkeysJanina Rzeznitzeck0Frederic J. Hoerr1Ivan Rychlik2Karen Methling3Michael Lalk4Alexandra Rath5Alexandra von Altrock6Silke Rautenschlein7Clinic for Poultry, University of Veterinary Medicine Hannover, Foundation, 30559 Hannover, GermanyVeterinary Diagnostic Pathology, Fort Valley, VA 22652, USAVeterinary Research Institute, 621 00 Brno, Czech RepublicInstitute of Biochemistry, University of Greifswald, 17487 Greifswald, GermanyInstitute of Biochemistry, University of Greifswald, 17487 Greifswald, GermanyClinic for Swine, Small Ruminants and Forensic Medicine, University of Veterinary Medicine Hannover, Foundation, 30173 Hannover, GermanyClinic for Swine, Small Ruminants and Forensic Medicine, University of Veterinary Medicine Hannover, Foundation, 30173 Hannover, GermanyClinic for Poultry, University of Veterinary Medicine Hannover, Foundation, 30559 Hannover, Germany; Corresponding author:ABSTRACT: The global turkey industry is confronted with emerging challenges regarding health and welfare. Performance and disease resilience are directly linked to gut health. A clear definition of a healthy gut is a prerequisite to developing new strategies for improved gut health and, thus, general health, welfare and productivity. To date, detailed knowledge about gut health characteristics, especially during the critical fattening period, is still lacking for turkeys. Therefore, the goal of this study was to describe the morphology, microbiota, and metabolome along the intestinal tract of clinically healthy Salmonella- and Campylobacter-free commercial turkey hens throughout the fattening period from 7 to 10 wk posthatch, and obtain information on the stability of the investigated values over time. Feed changes were avoided directly preceding and during the investigation period. Investigation methods included histomorphometric measurement of intestinal villi and crypts, Illumina-sequencing for microbiota analysis, and proton nuclear magnetic resonance spectroscopy for metabolite identification and quantification. Overall, the study demonstrated a high repeatability across all 3 experiments and gut section differences observed coincided with their functions. It was demonstrated that gut maturation, defined by gut microbiota stability, is reached earlier in the ceca than any other intestinal section where morphological changes are ongoing throughout the fattening period. Therefore, the present study provides valuable information necessary to advise future studies on the development and implementation of measures to support gut maturation and establish a protective microbiota in commercial turkeys.http://www.sciencedirect.com/science/article/pii/S0032579122003376turkeyagefatteninggut microbiotaintestinal metabolome |
| spellingShingle | Janina Rzeznitzeck Frederic J. Hoerr Ivan Rychlik Karen Methling Michael Lalk Alexandra Rath Alexandra von Altrock Silke Rautenschlein Morphology, microbiota, and metabolome along the intestinal tract of female turkeys Poultry Science turkey age fattening gut microbiota intestinal metabolome |
| title | Morphology, microbiota, and metabolome along the intestinal tract of female turkeys |
| title_full | Morphology, microbiota, and metabolome along the intestinal tract of female turkeys |
| title_fullStr | Morphology, microbiota, and metabolome along the intestinal tract of female turkeys |
| title_full_unstemmed | Morphology, microbiota, and metabolome along the intestinal tract of female turkeys |
| title_short | Morphology, microbiota, and metabolome along the intestinal tract of female turkeys |
| title_sort | morphology microbiota and metabolome along the intestinal tract of female turkeys |
| topic | turkey age fattening gut microbiota intestinal metabolome |
| url | http://www.sciencedirect.com/science/article/pii/S0032579122003376 |
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