Aquaporin-7: A Dynamic Aquaglyceroporin With Greater Water and Glycerol Permeability Than Its Bacterial Homolog GlpF

Aquaporin-7: A Dynamic Aquaglyceroporin With Greater Water and Glycerol Permeability Than Its Bacterial Homolog GlpF

Xenopus oocytes expressing human aquaporin-7 (AQP7) exhibit greater osmotic water permeability and 3H-glycerol uptake vs. those expressing the bacterial glycerol facilitator GlpF. AQP7-expressing oocytes exposed to increasing extracellular [glycerol] under isosmolal conditions exhibit increasing swe...

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Bibliographic Details
Main Authors: Fraser J. Moss, Paween Mahinthichaichan, David T. Lodowski, Thomas Kowatz, Emad Tajkhorshid, Andreas Engel, Walter F. Boron, Ardeschir Vahedi-Faridi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Physiology
Subjects:
AQP7
atomic structure
glycerol facilitator
molecular dynamics simulation
Xenopus oocytes
osmotic water permeability
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00728/full

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