L-Arginine Enhances Oral Keratinocyte Proliferation under High-Glucose Conditions via Upregulation of <i>CYP1A1</i>, <i>SKP2</i>, and <i>SRSF5</i>

L-Arginine Enhances Oral Keratinocyte Proliferation under High-Glucose Conditions via Upregulation of <i>CYP1A1</i>, <i>SKP2</i>, and <i>SRSF5</i>

High glucose inhibits oral keratinocyte proliferation. Diabetes can lead to delayed oral wound healing and periodontal disease. L-Arginine, one of the most versatile amino acids, plays an important role in wound healing, organ maturation, and development. In this study, L-Arginine was found to enhan...

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Bibliographic Details
Main Authors: Junhe Shi, Trevor R. Leonardo, Chen Han, Hiba I. Bangash, Dandan Chen, Harsh M. Trivedi, Lin Chen
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Molecules
Subjects:
L-Arginine
high glucose
oral keratinocyte
proliferation
<i>CYP1A1</i>
<i>SKP2</i>
Online Access:https://www.mdpi.com/1420-3049/28/20/7020

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