Lagging Strand Initiation Processes in DNA Replication of Eukaryotes—Strings of Highly Coordinated Reactions Governed by Multiprotein Complexes

Lagging Strand Initiation Processes in DNA Replication of Eukaryotes—Strings of Highly Coordinated Reactions Governed by Multiprotein Complexes

In their influential reviews, Hanahan and Weinberg coined the term ‘Hallmarks of Cancer’ and described genome instability as a property of cells enabling cancer development. Accurate DNA replication of genomes is central to diminishing genome instability. Here, the understanding of the initiation of...

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Bibliographic Details
Main Authors:	Heinz Peter Nasheuer, Nichodemus O. Onwubiko
Format:	Article
Language:	English
Published:	MDPI AG 2023-04-01
Series:	Genes
Subjects:	genome stability DNA replication lagging strand DNA synthesis Okazaki fragments initiation DNA polymerase α
Online Access:	https://www.mdpi.com/2073-4425/14/5/1012

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