Polymer nanocomposite prepared using copper oxide nanoparticles derived from Sterculia foetida leaf extract with biological applications

The new hydrogel network was prepared by using glutaric acid, ethylene glycol and acrylic acid (GEA) through condensation polymerization without cross linker and it was fabricated by incorporation of green synthesized CuO nanoparticles (CuO NPs). The CuO NPs were synthesized by green route using Ste...

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Main Authors: K Subashini, S Prakash, V Sujatha
Format: Article
Language:English
Published: IOP Publishing 2020-01-01
Series:Materials Research Express
Subjects:
Online Access:https://doi.org/10.1088/2053-1591/abc979
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author K Subashini
S Prakash
V Sujatha
author_facet K Subashini
S Prakash
V Sujatha
author_sort K Subashini
collection DOAJ
description The new hydrogel network was prepared by using glutaric acid, ethylene glycol and acrylic acid (GEA) through condensation polymerization without cross linker and it was fabricated by incorporation of green synthesized CuO nanoparticles (CuO NPs). The CuO NPs were synthesized by green route using Sterculia foetida leaf aqueous extract. Green synthesized CuO NPs were incorporated with GEA hydrogel resultant the GEA-CuO nanocomposite. The formation of green synthesized CuO NPs and GEA-CuO nanocomposite was confirmed by UV-Visible and FT-IR spectrum. The structure of GEA hydrogel was determined by ^1 H and ^13 C NMR technique. Morphology of synthesized GEA hydrogel and GEA-CuO nanocomposite was observed as bulged layer and uneven plates with cavities in SEM analysis, moreover the size of the material was evaluated by TEM analysis. Thermogravimetric analysis has revealed the GEA-CuO nanocomposite owing significantly higher thermal stability than raw GEA hydrogel. However, biological effect of synthesized GEA hydrogel and GEA-CuO nanocomposite was scrutinized by antibacterial activity against selected bacterial organisms and anticancer activity against lung cancer cell line A549.
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spelling doaj.art-35f32d5bccc54df494e825c4329e318b2023-08-09T15:52:10ZengIOP PublishingMaterials Research Express2053-15912020-01-0171111530810.1088/2053-1591/abc979Polymer nanocomposite prepared using copper oxide nanoparticles derived from Sterculia foetida leaf extract with biological applicationsK Subashini0S Prakash1V Sujatha2https://orcid.org/0000-0001-7663-7129Department of Chemistry, Periyar University , Salem-636 011, Tamil Nadu, India; Department of Chemistry, New Horizon College of Engineering, Bangalore-560103, Karnataka, IndiaDepartment of Chemistry, Periyar University , Salem-636 011, Tamil Nadu, IndiaDepartment of Chemistry, Periyar University , Salem-636 011, Tamil Nadu, IndiaThe new hydrogel network was prepared by using glutaric acid, ethylene glycol and acrylic acid (GEA) through condensation polymerization without cross linker and it was fabricated by incorporation of green synthesized CuO nanoparticles (CuO NPs). The CuO NPs were synthesized by green route using Sterculia foetida leaf aqueous extract. Green synthesized CuO NPs were incorporated with GEA hydrogel resultant the GEA-CuO nanocomposite. The formation of green synthesized CuO NPs and GEA-CuO nanocomposite was confirmed by UV-Visible and FT-IR spectrum. The structure of GEA hydrogel was determined by ^1 H and ^13 C NMR technique. Morphology of synthesized GEA hydrogel and GEA-CuO nanocomposite was observed as bulged layer and uneven plates with cavities in SEM analysis, moreover the size of the material was evaluated by TEM analysis. Thermogravimetric analysis has revealed the GEA-CuO nanocomposite owing significantly higher thermal stability than raw GEA hydrogel. However, biological effect of synthesized GEA hydrogel and GEA-CuO nanocomposite was scrutinized by antibacterial activity against selected bacterial organisms and anticancer activity against lung cancer cell line A549.https://doi.org/10.1088/2053-1591/abc979nanocompositethermal stabilityantibacterial activityanticancer activity
spellingShingle K Subashini
S Prakash
V Sujatha
Polymer nanocomposite prepared using copper oxide nanoparticles derived from Sterculia foetida leaf extract with biological applications
Materials Research Express
nanocomposite
thermal stability
antibacterial activity
anticancer activity
title Polymer nanocomposite prepared using copper oxide nanoparticles derived from Sterculia foetida leaf extract with biological applications
title_full Polymer nanocomposite prepared using copper oxide nanoparticles derived from Sterculia foetida leaf extract with biological applications
title_fullStr Polymer nanocomposite prepared using copper oxide nanoparticles derived from Sterculia foetida leaf extract with biological applications
title_full_unstemmed Polymer nanocomposite prepared using copper oxide nanoparticles derived from Sterculia foetida leaf extract with biological applications
title_short Polymer nanocomposite prepared using copper oxide nanoparticles derived from Sterculia foetida leaf extract with biological applications
title_sort polymer nanocomposite prepared using copper oxide nanoparticles derived from sterculia foetida leaf extract with biological applications
topic nanocomposite
thermal stability
antibacterial activity
anticancer activity
url https://doi.org/10.1088/2053-1591/abc979
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AT sprakash polymernanocompositepreparedusingcopperoxidenanoparticlesderivedfromsterculiafoetidaleafextractwithbiologicalapplications
AT vsujatha polymernanocompositepreparedusingcopperoxidenanoparticlesderivedfromsterculiafoetidaleafextractwithbiologicalapplications