First Phase of Glucose-Stimulated Insulin Secretion From MIN 6 Cells Does Not Always Require Extracellular Calcium Influx

Abstract.: To demonstrate an involvement of ATP-sensitive potassium (KATP) channel-independent pathways in the first phase of glucose-stimulated insulin secretion (GSIS) from pancreatic β cells, the time course of GSIS from MIN6 cells was analyzed at 30-s sample intervals. GSIS was biphasic with the...

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Bibliographic Details
Main Authors: Shigeto Makoto, Katsura Masashi, Matsuda Masafumi, Ohkuma Seitaro, Kaku Kohei
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319344330

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