Cartilage-targeting poly(ethylene glycol) (PEG)-formononetin (FMN) nanodrug for the treatment of osteoarthritis

Cartilage-targeting poly(ethylene glycol) (PEG)-formononetin (FMN) nanodrug for the treatment of osteoarthritis

Abstract Intra-articular (IA) injection is an efficient treatment for osteoarthritis, which will minimize systemic side effects. However, the joint experiences rapid clearance of therapeutics after intra-articular injection. Delivering system modified through active targeting strategies to facilitat...

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Bibliographic Details
Main Authors: Wei Xiong, Qiumei Lan, Xiaonan Liang, Jinmin Zhao, Hanji Huang, Yanting Zhan, Zainen Qin, Xianfang Jiang, Li Zheng
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Journal of Nanobiotechnology
Subjects:
Formononetin
PEG
Cartilage-targeting
Osteoarthritis
Online Access:https://doi.org/10.1186/s12951-021-00945-x

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