Nucleotide degradation and ribose salvage in yeast
Nucleotide degradation is a universal metabolic capability. Here we combine metabolomics, genetics and biochemistry to characterize the yeast pathway. Nutrient starvation, via PKA, AMPK/SNF1, and TOR, triggers autophagic breakdown of ribosomes into nucleotides. A protein not previously associated wi...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2013-01-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.1038/msb.2013.21 |