Canagliflozin and irbesartan ameliorate renal fibrosis via the TGF-β1/Smad signaling pathway in Dahl salt-sensitive rats
Objectives This study assessed the antifibrotic effects of canagliflozin, with or without irbesartan, on renal injury in Dahl salt-sensitive (SS) rats fed a high-salt (HS) diet. Methods After the preconditioning stage, Dahl SS rats (n = 47) were divided into five experimental groups as follows: low-...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2023-10-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605231206289 |