The Odyssey of Bioactive Compounds in Avocado (<i>Persea americana</i>) and Their Health Benefits

<i>Persea americana</i>, commonly known as avocado, has recently gained substantial popularity and is often marketed as a &#8220;superfood&#8221; because of its unique nutritional composition, antioxidant content, and biochemical profile. However, the term &#8220;superfood&am...

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Main Authors: Deep Jyoti Bhuyan, Muhammad A. Alsherbiny, Saumya Perera, Mitchell Low, Amrita Basu, Okram Abemsana Devi, Mridula Saikia Barooah, Chun Guang Li, Konstantinos Papoutsis
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/8/10/426
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author Deep Jyoti Bhuyan
Muhammad A. Alsherbiny
Saumya Perera
Mitchell Low
Amrita Basu
Okram Abemsana Devi
Mridula Saikia Barooah
Chun Guang Li
Konstantinos Papoutsis
author_facet Deep Jyoti Bhuyan
Muhammad A. Alsherbiny
Saumya Perera
Mitchell Low
Amrita Basu
Okram Abemsana Devi
Mridula Saikia Barooah
Chun Guang Li
Konstantinos Papoutsis
author_sort Deep Jyoti Bhuyan
collection DOAJ
description <i>Persea americana</i>, commonly known as avocado, has recently gained substantial popularity and is often marketed as a &#8220;superfood&#8221; because of its unique nutritional composition, antioxidant content, and biochemical profile. However, the term &#8220;superfood&#8221; can be vague and misleading, as it is often associated with unrealistic health claims. This review draws a comprehensive summary and assessment of research performed in the last few decades to understand the nutritional and therapeutic properties of avocado and its bioactive compounds. In particular, studies reporting the major metabolites of avocado, their antioxidant as well as bioavailability and pharmacokinetic properties, are summarized and assessed. Furthermore, the potential of avocado in novel drug discovery for the prevention and treatment of cancer, microbial, inflammatory, diabetes, and cardiovascular diseases is highlighted. This review also proposes several interesting future directions for avocado research.
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spelling doaj.art-360908dd26c34e2aacd6552d4e97990d2023-09-03T03:20:47ZengMDPI AGAntioxidants2076-39212019-09-0181042610.3390/antiox8100426antiox8100426The Odyssey of Bioactive Compounds in Avocado (<i>Persea americana</i>) and Their Health BenefitsDeep Jyoti Bhuyan0Muhammad A. Alsherbiny1Saumya Perera2Mitchell Low3Amrita Basu4Okram Abemsana Devi5Mridula Saikia Barooah6Chun Guang Li7Konstantinos Papoutsis8NICM Health Research Institute, Western Sydney University, Penrith, NSW 2751, AustraliaNICM Health Research Institute, Western Sydney University, Penrith, NSW 2751, AustraliaNICM Health Research Institute, Western Sydney University, Penrith, NSW 2751, AustraliaNICM Health Research Institute, Western Sydney University, Penrith, NSW 2751, AustraliaResearch Centre for Toxic Compounds in the Environment, Masaryk University, Brno 62500, CzechDepartment of Food Science and Nutrition, College of Community Science, Assam Agricultural University, Assam 785013, IndiaDepartment of Food Science and Nutrition, College of Community Science, Assam Agricultural University, Assam 785013, IndiaNICM Health Research Institute, Western Sydney University, Penrith, NSW 2751, AustraliaSchool of Agriculture and Food Science, University College Dublin, Belfield, Dublin 4, Ireland<i>Persea americana</i>, commonly known as avocado, has recently gained substantial popularity and is often marketed as a &#8220;superfood&#8221; because of its unique nutritional composition, antioxidant content, and biochemical profile. However, the term &#8220;superfood&#8221; can be vague and misleading, as it is often associated with unrealistic health claims. This review draws a comprehensive summary and assessment of research performed in the last few decades to understand the nutritional and therapeutic properties of avocado and its bioactive compounds. In particular, studies reporting the major metabolites of avocado, their antioxidant as well as bioavailability and pharmacokinetic properties, are summarized and assessed. Furthermore, the potential of avocado in novel drug discovery for the prevention and treatment of cancer, microbial, inflammatory, diabetes, and cardiovascular diseases is highlighted. This review also proposes several interesting future directions for avocado research.https://www.mdpi.com/2076-3921/8/10/426avocado<i>Persea americana</i>metabolitesantioxidantsanticancerantimicrobialanti-inflammatorydiabetescardiovascular diseases (CVD)bioavailability and pharmacokinetic
spellingShingle Deep Jyoti Bhuyan
Muhammad A. Alsherbiny
Saumya Perera
Mitchell Low
Amrita Basu
Okram Abemsana Devi
Mridula Saikia Barooah
Chun Guang Li
Konstantinos Papoutsis
The Odyssey of Bioactive Compounds in Avocado (<i>Persea americana</i>) and Their Health Benefits
Antioxidants
avocado
<i>Persea americana</i>
metabolites
antioxidants
anticancer
antimicrobial
anti-inflammatory
diabetes
cardiovascular diseases (CVD)
bioavailability and pharmacokinetic
title The Odyssey of Bioactive Compounds in Avocado (<i>Persea americana</i>) and Their Health Benefits
title_full The Odyssey of Bioactive Compounds in Avocado (<i>Persea americana</i>) and Their Health Benefits
title_fullStr The Odyssey of Bioactive Compounds in Avocado (<i>Persea americana</i>) and Their Health Benefits
title_full_unstemmed The Odyssey of Bioactive Compounds in Avocado (<i>Persea americana</i>) and Their Health Benefits
title_short The Odyssey of Bioactive Compounds in Avocado (<i>Persea americana</i>) and Their Health Benefits
title_sort odyssey of bioactive compounds in avocado i persea americana i and their health benefits
topic avocado
<i>Persea americana</i>
metabolites
antioxidants
anticancer
antimicrobial
anti-inflammatory
diabetes
cardiovascular diseases (CVD)
bioavailability and pharmacokinetic
url https://www.mdpi.com/2076-3921/8/10/426
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