FOXC1 Negatively Regulates DKK1 Expression to Promote Gastric Cancer Cell Proliferation Through Activation of Wnt Signaling Pathway

FOXC1 Negatively Regulates DKK1 Expression to Promote Gastric Cancer Cell Proliferation Through Activation of Wnt Signaling Pathway

Gastric cancer (GC), characterized by uncontrolled growth, is a common malignant tumor of the digestive system. The Wnt signaling pathway plays an important role in the tumorigenesis and proliferation of GC. Many studies on this signaling pathway have focused on its intracellular regulatory mechanis...

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Bibliographic Details
Main Authors: Jiang Jiang, Jianfang Li, Weiwu Yao, Wenfang Wang, Bowen Shi, Fei Yuan, Jingyan Dong, Huan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
gastric cancer
FOXC1
DKK1
c-MYC
proliferation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.662624/full

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