Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseases
The human intestine hosts diverse microbial communities that play a significant role in maintaining gut-skin homeostasis. When the relationship between gut microbiome and the immune system is impaired, subsequent effects can be triggered on the skin, potentially promoting the development of skin dis...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2022-12-01
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| Series: | Gut Microbes |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/19490976.2022.2096995 |
| _version_ | 1817971419918630912 |
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| author | Md. Rayhan Mahmud Sharmin Akter Sanjida Khanam Tamanna Lincon Mazumder Israt Zahan Esti Sanchita Banerjee Sumona Akter Md. Rakibul Hasan Mrityunjoy Acharjee Md. Sajjad Hossain Anna Maria Pirttilä |
| author_facet | Md. Rayhan Mahmud Sharmin Akter Sanjida Khanam Tamanna Lincon Mazumder Israt Zahan Esti Sanchita Banerjee Sumona Akter Md. Rakibul Hasan Mrityunjoy Acharjee Md. Sajjad Hossain Anna Maria Pirttilä |
| author_sort | Md. Rayhan Mahmud |
| collection | DOAJ |
| description | The human intestine hosts diverse microbial communities that play a significant role in maintaining gut-skin homeostasis. When the relationship between gut microbiome and the immune system is impaired, subsequent effects can be triggered on the skin, potentially promoting the development of skin diseases. The mechanisms through which the gut microbiome affects skin health are still unclear. Enhancing our understanding on the connection between skin and gut microbiome is needed to find novel ways to treat human skin disorders. In this review, we systematically evaluate current data regarding microbial ecology of healthy skin and gut, diet, pre- and probiotics, and antibiotics, on gut microbiome and their effects on skin health. We discuss potential mechanisms of the gut-skin axis and the link between the gut and skin-associated diseases, such as psoriasis, atopic dermatitis, acne vulgaris, rosacea, alopecia areata, and hidradenitis suppurativa. This review will increase our understanding of the impacts of gut microbiome on skin conditions to aid in finding new medications for skin-associated diseases. |
| first_indexed | 2024-04-13T20:47:01Z |
| format | Article |
| id | doaj.art-360a3922f7a54462a40052b1a8f5cb5c |
| institution | Directory Open Access Journal |
| issn | 1949-0976 1949-0984 |
| language | English |
| last_indexed | 2024-04-13T20:47:01Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Gut Microbes |
| spelling | doaj.art-360a3922f7a54462a40052b1a8f5cb5c2022-12-22T02:30:39ZengTaylor & Francis GroupGut Microbes1949-09761949-09842022-12-0114110.1080/19490976.2022.2096995Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseasesMd. Rayhan Mahmud0Sharmin Akter1Sanjida Khanam Tamanna2Lincon Mazumder3Israt Zahan Esti4Sanchita Banerjee5Sumona Akter6Md. Rakibul Hasan7Mrityunjoy Acharjee8Md. Sajjad Hossain9Anna Maria Pirttilä10Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, FinlandDepartment of Microbiology, Jagannath University, Dhaka, BangladeshDepartment of Microbiology, Jagannath University, Dhaka, BangladeshDepartment of Microbiology, Jagannath University, Dhaka, BangladeshDepartment of Microbiology, Jagannath University, Dhaka, BangladeshDepartment of Microbiology, Jagannath University, Dhaka, BangladeshDepartment of Microbiology, Jagannath University, Dhaka, BangladeshDepartment of Microbiology, Jagannath University, Dhaka, BangladeshDepartment of Bioscience, Graduate School of Science and Technology, Shizuoka University, Shizuoka, JapanInstitute of Biology, Eötvös Loránd University, Budapest, HungaryEcology and Genetics, Faculty of Science, University of Oulu, Oulu, FinlandThe human intestine hosts diverse microbial communities that play a significant role in maintaining gut-skin homeostasis. When the relationship between gut microbiome and the immune system is impaired, subsequent effects can be triggered on the skin, potentially promoting the development of skin diseases. The mechanisms through which the gut microbiome affects skin health are still unclear. Enhancing our understanding on the connection between skin and gut microbiome is needed to find novel ways to treat human skin disorders. In this review, we systematically evaluate current data regarding microbial ecology of healthy skin and gut, diet, pre- and probiotics, and antibiotics, on gut microbiome and their effects on skin health. We discuss potential mechanisms of the gut-skin axis and the link between the gut and skin-associated diseases, such as psoriasis, atopic dermatitis, acne vulgaris, rosacea, alopecia areata, and hidradenitis suppurativa. This review will increase our understanding of the impacts of gut microbiome on skin conditions to aid in finding new medications for skin-associated diseases.https://www.tandfonline.com/doi/10.1080/19490976.2022.2096995Gut microbiomegastrointestinal healthgut dysbiosisskin diseaseprobioticsprebiotics |
| spellingShingle | Md. Rayhan Mahmud Sharmin Akter Sanjida Khanam Tamanna Lincon Mazumder Israt Zahan Esti Sanchita Banerjee Sumona Akter Md. Rakibul Hasan Mrityunjoy Acharjee Md. Sajjad Hossain Anna Maria Pirttilä Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseases Gut Microbes Gut microbiome gastrointestinal health gut dysbiosis skin disease probiotics prebiotics |
| title | Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseases |
| title_full | Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseases |
| title_fullStr | Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseases |
| title_full_unstemmed | Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseases |
| title_short | Impact of gut microbiome on skin health: gut-skin axis observed through the lenses of therapeutics and skin diseases |
| title_sort | impact of gut microbiome on skin health gut skin axis observed through the lenses of therapeutics and skin diseases |
| topic | Gut microbiome gastrointestinal health gut dysbiosis skin disease probiotics prebiotics |
| url | https://www.tandfonline.com/doi/10.1080/19490976.2022.2096995 |
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