Zinc-responsive acral hyperkeratosis: A report of a rare entity
Chronic acral hyperkeratotic dermatosis includes several conditions such as lichen simplex chronicus (LSC), hypertrophic lichen planus (HLP), psoriasis vulgaris (Ps), acral acanthosis nigricans, acquired zinc deficiency, and necrolytic acral erythema (NAE). LSC, Ps, and HLP respond to conventional t...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Indian Dermatology Online Journal |
| Subjects: | |
| Online Access: | http://www.idoj.in/article.asp?issn=2229-5178;year=2021;volume=12;issue=6;spage=892;epage=895;aulast=Kowe |
| _version_ | 1811239440808411136 |
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| author | Priyanka A Kowe Ravi Bhushan Vaishali H Wankhade Rajesh P Singh |
| author_facet | Priyanka A Kowe Ravi Bhushan Vaishali H Wankhade Rajesh P Singh |
| author_sort | Priyanka A Kowe |
| collection | DOAJ |
| description | Chronic acral hyperkeratotic dermatosis includes several conditions such as lichen simplex chronicus (LSC), hypertrophic lichen planus (HLP), psoriasis vulgaris (Ps), acral acanthosis nigricans, acquired zinc deficiency, and necrolytic acral erythema (NAE). LSC, Ps, and HLP respond to conventional treatments such as topical corticosteroids, immuno-modulators such as tacrolimus, and oral methotrexate. Zinc-responsive acral hyperkeratosis is a novel entity that resembles the above mentioned diagnoses clinically but fails to respond to the above treatment options. NAE is a rare condition, commonly associated with hepatitis C virus infection and manifest similar clinical features of zinc-responsive acral hyperkeratosis, but differs histopathologically. Both conditions show a good response to oral zinc supplementation. As there is a paucity of literature on zinc-responsive acral hyperkeratosis, we are highlighting the case. |
| first_indexed | 2024-04-12T13:01:27Z |
| format | Article |
| id | doaj.art-360a773ee34e45d6a7928f9ec95b2130 |
| institution | Directory Open Access Journal |
| issn | 2229-5178 |
| language | English |
| last_indexed | 2024-04-12T13:01:27Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Dermatology Online Journal |
| spelling | doaj.art-360a773ee34e45d6a7928f9ec95b21302022-12-22T03:32:09ZengWolters Kluwer Medknow PublicationsIndian Dermatology Online Journal2229-51782021-01-0112689289510.4103/idoj.IDOJ_557_20Zinc-responsive acral hyperkeratosis: A report of a rare entityPriyanka A KoweRavi BhushanVaishali H WankhadeRajesh P SinghChronic acral hyperkeratotic dermatosis includes several conditions such as lichen simplex chronicus (LSC), hypertrophic lichen planus (HLP), psoriasis vulgaris (Ps), acral acanthosis nigricans, acquired zinc deficiency, and necrolytic acral erythema (NAE). LSC, Ps, and HLP respond to conventional treatments such as topical corticosteroids, immuno-modulators such as tacrolimus, and oral methotrexate. Zinc-responsive acral hyperkeratosis is a novel entity that resembles the above mentioned diagnoses clinically but fails to respond to the above treatment options. NAE is a rare condition, commonly associated with hepatitis C virus infection and manifest similar clinical features of zinc-responsive acral hyperkeratosis, but differs histopathologically. Both conditions show a good response to oral zinc supplementation. As there is a paucity of literature on zinc-responsive acral hyperkeratosis, we are highlighting the case.http://www.idoj.in/article.asp?issn=2229-5178;year=2021;volume=12;issue=6;spage=892;epage=895;aulast=Koweacral hyperkeratosishepatitis c infectionnecrolytic acral erythemazinc |
| spellingShingle | Priyanka A Kowe Ravi Bhushan Vaishali H Wankhade Rajesh P Singh Zinc-responsive acral hyperkeratosis: A report of a rare entity Indian Dermatology Online Journal acral hyperkeratosis hepatitis c infection necrolytic acral erythema zinc |
| title | Zinc-responsive acral hyperkeratosis: A report of a rare entity |
| title_full | Zinc-responsive acral hyperkeratosis: A report of a rare entity |
| title_fullStr | Zinc-responsive acral hyperkeratosis: A report of a rare entity |
| title_full_unstemmed | Zinc-responsive acral hyperkeratosis: A report of a rare entity |
| title_short | Zinc-responsive acral hyperkeratosis: A report of a rare entity |
| title_sort | zinc responsive acral hyperkeratosis a report of a rare entity |
| topic | acral hyperkeratosis hepatitis c infection necrolytic acral erythema zinc |
| url | http://www.idoj.in/article.asp?issn=2229-5178;year=2021;volume=12;issue=6;spage=892;epage=895;aulast=Kowe |
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