A therapeutic chimeric IgG/IgA expressed by CHO cells for oral treatment of PED in piglets

Immunoglobulin A (IgA) of sows is critically important for assessing piglets’ protective capacity against porcine epidemic diarrhea virus (PEDV). Here, we report a therapeutic chimeric anti-PEDV IgG/IgA expressed by Chinese hamster ovary (CHO) cells for oral treatment of PED. The chimeric anti-PEDV...

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Bibliographic Details
Main Authors: Yan Xiao, Yunjing Zhang, Zhiyan Wang, Wenyin Zhao, Xin Xu, Xiao Chen, Feifei Tan, Zhe Sun, Baicheng Huang, Kegong Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1018748/full