Evaluation of secretomes derived from human dermal and adipose tissue mesenchymal stem/stromal cells for skin wound healing: not as effective as cells

Evaluation of secretomes derived from human dermal and adipose tissue mesenchymal stem/stromal cells for skin wound healing: not as effective as cells

Abstract Background Although the paracrine effects of mesenchymal stem/stromal cells (MSCs) have been recognized as crucial mediators of their regenerative effects on tissue repair, the potential of MSC secretomes as effective substitutes for cellular therapies remains underexplored. Methods In this...

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Main Authors: Helena Debiazi Zomer, Victor Juan de Souza Lima, Monique Coelho Bion, Karynne Nazare Lins Brito, Michele Rode, Marco Augusto Stimamiglio, Talita da Silva Jeremias, Andrea Gonçalves Trentin
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Stem Cell Research & Therapy
Subjects:
MSC
Dermis
Conditioned medium
Exosomes
Integra matrix
Proteomic
Online Access:https://doi.org/10.1186/s13287-023-03630-y

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